Newsweek (1/8, Moyler) reports investigators “have identified six genetic variants linked to the development of anxiety disorders” after examining “genetic and health data derived from 200,000 veterans of the United States Armed Forces, which was compiled in the Million Veteran Program.” Five of the “six genetic variants associated with higher risks of developing anxiety disorders” were “found in white Americans, while an additional one was found in black Americans.” The variants “were found on chromosomes 1, 3, 6, 7 and 20,” and “the one on chromosome 7, was previously identified to be correlated with higher occurrences of bipolar disorder and schizophrenia.”
Medscape (1/8, Brooks, Subscription Publication) reports, “In European Americans, the two strongest anxiety-related loci were on chromosome 3 near special AT-rich sequence-binding protein-1 (SATB1), a global regulator of gene expression that influences expression of multiple genes involved neuronal development, and on chromosome 6 near estrogen receptor alpha (ESR1), which encodes” a receptor for estrogen. Even though “this finding might help explain why women are more than twice as likely as men to suffer from anxiety, the researchers note that they identified the variant affecting estrogen receptors in a veteran cohort made up mostly of men, and that further investigation is needed.” The findings were published online Jan. 7 in the American Journal of Psychiatry, a publication of the American Psychiatric Association.
Related Links:
— “Scientists Discover Six Genetic Links To Anxiety In Largest-Ever Study On Subject, “Hunter Moyler, Newsweek, January 8, 2020