Medscape (6/29, Lowry) reports, “Good physical fitness at age 18 years is associated with a reduced risk for serious depression later in life,” according to a study involving some 1.1 million men in Sweden that was published online June 14 in the British Journal of Psychiatry. Notably, “after controlling for factors that included body mass index, conscription test center, and familial factors, the hazard ratio (HR) associated with lower cardiovascular [CV] fitness at age 18 for serious depression in adulthood was 1.96 (95% confidence interval [CI], 1.71 – 2.23).” However, “there was no such association found for bipolar disorder (HR, 1.11; 95% CI, 0.84 – 1.47).”