MedPage Today (8/2, DePeau-Wilson) reports “continuing adjunctive antidepressant treatment for up to a year following remission of an acute depressive episode in patients with bipolar I disorder showed no significant benefit for preventing relapse, a randomized trial showed.” At 52 weeks, about “31% of patients treated with maintenance escitalopram (Lexapro) or bupropion XL (Wellbutrin XL) for that duration of time experienced a subsequent mood episode, as compared with 46% of those who switched to placebo at 8 weeks.” The findings were published online in the New England Journal of Medicine.
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