Antidepressant Use Linked To Long-Term Weight Gain, Study Finds

Medscape (3/27, Cotelo, Subscription Publication) reports a study found “the use of antidepressants has been linked to a 2% weight gain in patients who used this treatment at any point during a 6-year follow-up.” According to researchers, “the average weight gain after 6 years was 0.53 kg (1.01% of body weight), and 24.5% of participants gained more than 5% of their body weight.” They said the “data indicate that women, individuals under 55, and those with normal weight at the start of the study were more likely to experience” weight gain with antidepressant use. They concluded, “All individuals taking antidepressants had a higher likelihood of weight gain and developing obesity, with the risk increasing for those with continued use of these medications.” The study was published in Frontiers in Psychiatry.

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