Patients With Autoimmune Conditions Face Greater Risk For Mental Health Disorders, Study Finds

Healio (9/15, Wursta) reports a study found that “patients with autoimmune conditions and chronic inflammation may be at twice the risk for mental health disorders such as depression, bipolar disorder and anxiety vs. the general population.” The researchers “examined data from the Our Future Health research cohort, which included 1,563,155 participants…in the United Kingdom. Among the cohort, 37,808 patients had lifetime diagnoses of one of six autoimmune conditions: rheumatoid arthritis, Graves’ syndrome, inflammatory bowel disease, lupus, multiple sclerosis and psoriasis.” The researchers observed that “patients with an autoimmune condition demonstrated significantly higher rates of depression (28.8% vs. 17.9%), bipolar disorder (28.4% vs. 17.8%) and anxiety (29.3% vs. 18%) compared with healthy participants. The researchers additionally found risk for mental health issues in this patient group remained higher even after controlling for variables such as income, history of chronic pain and history of social isolation.” The study was published in BMJ Mental Health.

Related Links:

— “Anxiety, bipolar disorder risks nearly twice as high in patients with autoimmune disease,”Max R. Wursta, Healio , September 15, 2025

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