Medscape (10/11, Davenport, Subscription Publication) reports on a study presented at the European College of Neuropsychopharmacology Congress and published in Psychoneuroendocrinology finding that “childhood trauma, particularly sexual abuse, is more common in those with anxious depression and causes permanent biological changes that may explain poorer responses to standard treatment in this patient population.” The study included 144 “patients with major depressive disorder” and found “that those with anxious depression were almost twice as likely to have suffered sexual abuse in childhood and were 1.3 times more likely to have experienced emotional neglect than those with depression that was not accompanied by anxiety.”
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— Medscape (requires login and subscription)