Healio (7/16, Gramigna) reported, “One-fourth of people at clinical high risk for psychosis developed psychosis within three years,” investigators concluded in “an updated meta-analysis” that “included 130 longitudinal studies that reported transition risks among a total of 9,222 individuals at clinical high risk for psychosis (mean age, 20.3 years; 55.3% men).” The findings were published online July 14 in JAMA Psychiatry.
“ Risk of transitioning to psychosis was higher in studies with a lower proportion of female individuals and a higher proportion of individuals presenting with brief limited intermittent psychotic symptoms.
Meaning This updated meta-analysis indicates that the probability of transitioning to psychosis in individuals at clinical high risk is substantial and continues increasing in the long term, suggesting that an extended duration of clinical monitoring and preventive care may be beneficial.”
Related Links:
— “25% of people at clinical high risk for psychosis develop the disorder within 3 years “Joe Gramigna, Healio, July 16, 2021