Bipolar Disorder, Its Treatments Appear To Have Very Different Implications For Bone Health, Researchers Say

MedPage Today (3/30, Monaco) reports, “Bipolar disorder and its treatments may have very different implications for bone health,” investigators concluded. In the “retrospective cohort study,” researchers found that “among nearly 23,000 patients with bipolar disorder, the incidence rate of osteoporosis was 8.70 per 1,000 person-years compared with 7.90 per 1,000 person-years for an age- and sex-matched reference group.” The study also revealed, however, that “certain treatments for bipolar disorder appeared to not only offset this risk, but significantly reduce it.” In fact, “in a fully adjusted model, those with bipolar disorder who were on lithium – 38.2% of patients – saw a reduced risk for osteoporosis compared with those not on lithium.” The findings were published online March 30 in JAMA Psychiatry.

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