Preschoolers Prone To Tantrums Appear To Have Higher Risk Of ADHD By The Time They Reach School Age, Study Finds

HealthDay (11/26, Thompson ) reports, “Preschoolers prone to tantrums appear to have a higher risk of attention-deficit/hyperactivity disorder (ADHD) by the time they reach school age, a new study says.” Investigators found that “young children who struggle to control their emotions and behavior have more ADHD symptoms by age 7.” The study indicated that “their conduct is more likely to be poor and they are more apt to suffer from emotional problems like sadness or worry by that age.” The findings were published in Development and Psychopathology.

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— “Preschoolers’ Tantrums Can Be Early Sign of ADHD,” Dennis Thompson, HealthDay, November 26, 2024

High-Dose Antipsychotic Use For Schizophrenia Was Associated With Increased Mortality Risk, Study Indicates

HCPlive (11/26, Derman) reports, “A new study indicated high-dose antipsychotic use for schizophrenia was associated with increased mortality risk.” Investigators came to this conclusion after analyzing data on “32,240 patients aged 17 – 64 years…diagnosed with schizophrenia between January 1, 2002, and December 31, 2012.” The findings were published in JAMA Network Open.

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— “Can Antipsychotics Increase Mortality Risk? A New Study Shows It Might,” Chelsie Derman, HCPLive, November 26, 2024

Flight Passengers Can Experience Ongoing Mental, Physical Distress After Emergencies

The New York Times (11/25, Lewis) reports that following an incident last January on an Alaska Airlines flight in which “one of the plane’s doors had blown off,” over “30 other passengers from the Alaska Airlines flight are suing the carrier and Boeing, the aircraft manufacturer, citing ‘severe stress, anxiety, trauma, physical pain, flashbacks and fear of flying and also objective physical manifestations such as sleeplessness, PTSD, hearing damage and other injuries.’”

Such “harm inflicted on passengers who experienced in-flight emergencies…ha s not been as researched or recognized.” The Times adds, “Neither the Federal Aviation Administration nor the National Transportation Safety Board has policies or recommendations regarding passenger mental health after emergencies.”

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— “The New York Times (requires login and subscription)

Lack Of Control Over Work Environment Fosters Burnout Among Physicians, Study Finds

MedPage Today (11/25, DePeau-Wilson ) reports, “Lack of control over their work environment fostered burnout among physicians, along with an increased desire to bail out of the organization, according to a multi-institutio nal study.” An “analysis of data from 2,339 physicians revealed that those who reported having poor control over their workload had higher levels of burnout (OR 3.83, 95% CI 2.99-4.90),” according to investigators. The findings were published in Annals of Internal Medicine.

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MedPage Today (requires login and subscription)

Short-Term Menopausal Hormone Therapy Does Not Have Long-Term Cognitive Effects, Study Suggests

Psychiatric News (11/22) reported, “Short-term menopausal hormone therapy does not appear to have any long-term cognitive effects, either positive or negative, according to a study.” The researchers said the findings “may reassure women opting to use hormone therapy in early menopause, to manage menopausal symptoms, that 4 years of therapy started within 3 years of menopause had no long-term deleterious impact on cognition.” The findings were published in PLOS Medicine.

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— “Short-Term Menopausal Hormone Therapy Does Not Affect Long-Term Cognition, Study Finds,” Psychiatric News , November 22, 2024

Endo Expands Clonazepam Recall After Discovering Some Pills Were Labeled With Wrong Strength

The New York Times (11/22, Schmall ) reported, “A company that makes clonazepam, a drug commonly prescribed for anxiety and seizures, has expanded its recall of some of the pills after it discovered that they were labeled with the wrong strength, the Food and Drug Administration announced.” According to the Times, “the company, Endo, recalled 16 product lots of clonazepam, a drug best known by the brand name Klonopin.” Endo “said it had not received any reports of adverse events related to the recall.”

Related Links: — “The New York Times (requires login and subscription)

About 70% of Americans prefer to be asked about both physical health and mental health during PCP appointments

Medical Economics (11/21, Littrell) reports, “More than one in five U.S. adults, which equates to 59.3 million people, were living with mental illnesses in 2022, yet just more than half of them (50.6%) had received treatment in the previous year.” A new study, from Gallup and West Health, “uncovered that 70% of Americans would prefer to be asked about both their physical health and their mental health during appointments with their primary care providers (PCPs).” The survey “reported that 65% of men and 76% of women hoped to discuss both physical and mental health with their PCPs.” The research “also found that 66% of U.S. adults have been asked about their mental health by their PCPs or family practitioners, whereas 32% of adults said that had never happened.”

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— “70% of Americans want primary care providers to address mental health,” Austin Littrell, Medical Economics, November 21, 2024

Reaching Same Age At Which Parent Died By Suicide Increases Risk Of Suicide, Self-Harm Among Offspring, Study Suggests

Psychiatric News (11/21) reports “several studies have shown that individuals with a parent who died by suicide have an increased risk of suicide or self-harm themselves compared with individuals with living parents or a parent who died from other causes,” but a new study “now finds that this risk may be particularly elevated when the individual reaches the same age at which the parent died by suicide.” The researchers said, “Our findings support the idea of a dynamic process of grief, in so much as the elevated risk of suicidal behavior at [parental] age correspondence might also represent a period of loss orientation and increased distress.” The findings were published in Suicide and Life-Threatening Behavior.

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— “Reaching Age at Which Parent Died by Suicide Increases Suicide Risk Among Offspring,” Psychiatric News, November 21, 2024

Changes In Drug Supply Leading To Decrease In Overdose Deaths, Experts Say

The New York Times (11/21, Hoffman , Weiland ) reports, “After years of relentless rises in overdose deaths, the United States has seen a remarkable reversal.” For seven consecutive “months, according to federal data, drug fatalities have been declining.” Expanded prevention, treatment, “and education efforts are playing a role, but drug policy experts believe there is another, surprising reason: changes in the drug supply itself, which are, in turn, influencing how people are using drugs.” For example, “the fentanyl on the street is starting to become weaker.” According to addiction experts, “other interventions contributed to the declining fatalities, including wider distribution of overdose reversal medications” and “an uptick in some states in prescriptions for medication that suppresses opioid cravings.”

CNN (11/21, McPhillips ) reports, “The US Drug Enforcement Administration says that less fentanyl is present in the nation’s illicit pill supply and that is helping drive down overdose deaths in the United States.” However, “experts say that there are limitations to this claim and that many other factors are probably playing a role.”

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— “Less-potent fentanyl pills may be playing a role in decrease of US overdose deaths, DEA says,” Deidre McPhillips, CNN, November 21, 2024

FDA Panel Votes Against Key Provisions Of Clozapine REMS

Psychiatric News reports, “A panel convened by the Food and Drug Administration (FDA) voted overwhelmingly…against key provisions of the Clozapine Risk Evaluation and Mitigation Strategy (REMS) after hearing from clinicians, patients, and caregivers who said access to this effective schizophrenia medication was thwarted by red tape.” The FDA “panel voted 14-1 against the REMS requirement that prescribers document and pharmacies verify patients’ absolute neutrophil counts (ANC) before dispensing clozapine.” Additionally, the panel “voted 14-1 against the need for educating prescribers and pharmacists on the risk of clozapine-induced severe neutropenia and ANC monitoring.”

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— “FDA Panel Votes 14-1 Against Clozapine REMS,” Psychiatric News, November20 , 2024