CBS News (8/31, Saint Louis) publishes a KFF article that reports, “Since the National Suicide Prevention Lifeline transitioned a year ago to the three-digit crisis phone number 988, there has been a 33% increase in the number of calls, chats, and texts to the hotline.” But “even with that early sign of success, the program’s financial future is shaky.” Although “the federal government has provided about $1 billion…to launch the number,” after that, “it’s up to states to foot the bill for their call centers.”

Related Links:

— “Most states have yet to permanently fund 988 Lifeline despite early successes,”Christina Saint Louis, CBS News, August 31, 2023

Healio (8/31, Weldon) reports, “Depression among children did not increase substantially between 2004 and 2019, according to the” findings of a 41-study systematic review and meta-analysis published online Aug. 28 in JAMA Pediatrics.

Related Links:

— “Study: Depression among children ‘uncommon’ in years before pandemic,”Rose Weldon, Healio, August 31, 2023

Healio (8/30, Hornick) reports, “The impact of COVID-19 extends beyond those who get infected and evokes symptoms of anxiety, depression and PTSD in their families, according to two studies published in Annals of the American Thoracic Society.” In one study, investigators “analyzed 90 families of patients who had COVID-19 between September 2020 and April 2021 to determine the prevalence of anxiety, depression and stress while their relative was in the ICU compared with after their time in the ICU.” In the other study, researchers “assessed 115…family members of patients with COVID-19 in the ICU across five states to understand how PTSD symptoms vary at different times points within 1 year of their relative entering the ICU.”

Related Links:

— “Families of patients with COVID-19 suffer with anxiety, depression, PTSD,”Isabella Hornick, Healio, August 31, 2023

The New York Times (8/30, Hoffman, Weiland) reports, “Narcan, the first opioid overdose reversal medication approved for over-the-counter purchase, is being shipped to drugstore and grocery chains nationwide, its manufacturer said Wednesday.” Earlier this summer, the FDA “gave over-the-counter approval to RiVive, a naloxone spray expected in early 2024. RiVive, manufactured by Harm Reduction Therapeutics, is intended as a low-cost product largely for outreach groups.” Pharmacies at “Walgreens, CVS, Walmart and Rite Aid said they expected Narcan to be available online and on many store shelves early next week.”

NBC News (8/30, Lovelace) reports the FDA’s approval means the drug “can be sold in even more places, including…airports and even vending machines.” It “could also be available to buy online from some businesses this week.” However, its price tag of $44.99 for two doses “may put it out of reach for some.”

CNN (8/30, Tirrell, Kounang) also reports.

Related Links:

— “Narcan Is Headed to Stores: What You Need to Know,”Jan Hoffman and Noah Weiland, The New York Times , August 30, 2023

CNN (8/29, Howard) reports, “A group of novel synthetic opioids emerging in illicit drugs in the United States may be more powerful than fentanyl, 1,000 times more potent than morphine, and may even require more doses of the medication naloxone to reverse an overdose, a new study suggests.” The new opioid, nitazenes, “are a synthetic opioid, like fentanyl, although the two drugs are not structurally related. In the small study published Tuesday in the journal JAMA Network Open most of the patients who overdosed on nitazenes received two or more doses of the opioid overdose reversal drug naloxone, whereas most patients who overdosed on fentanyl received only a single dose of naloxone.”

Related Links:

— “Emerging group of synthetic opioids may be more potent than fentanyl, study warns,”Jacqueline Howard, CNN, August 29, 2023

mHealth Intelligence (8/29, Vaidya) reports, “Telemental healthcare utilization, which skyrocketed during the COVID-19 pandemic, remains ‘persistent and elevated,’ according to new research.” A study “published in JAMA Health Forum detailed an assessment of monthly telehealth and in-person utilization and spending for mental health services among commercially insured US adults between 2019 and 2022.” The research “shows that in-person visits decreased by 39.5 percent, and telehealth visits increased roughly ten-fold by 1,019.3 percent during the acute phase compared with the year prior.” Overall, “this represents a 22.3 percent increase in overall utilization of mental health services.”

Related Links:

— “Telemental Healthcare Grew Ten-Fold During Pandemic, Remains ‘Elevated’,”Anuja Vaidya, mHealth Intelligence, August 29, 2023

MedPage Today (8/29, DePeau-Wilson) reports, “Therapeutic doses of some selective serotonin reuptake inhibitors (SSRIs) may lead to cardiotoxic concentration levels associated with increased risk of arrhythmia in certain groups of patients, including those 65 and up,” investigators concluded in the findings of a 19,742-patient study published online ahead of print in the journal eBioMedicine. For the study, “patients had to have a” therapeutic drug monitoring “measurement of escitalopram or citalopram within the limits of quantification for inclusion.” The study revealed that in “patients 65 and over taking escitalopram (Lexapro) daily, about 20% were predicted to reach potentially pro-arrhythmic concentrations with a 10-mg dose, which increased to about 60% with a 20-mg dose.”

Related Links:

— MedPage Today (requires login and subscription)

The New York Times (8/29, Richtel) reports, “More than one-fifth of people who use cannabis struggle with dependency or problematic use, according to” findings published online Aug. 29 in JAMA Network Open. The study, which “drew its data from nearly 1,500 primary care patients in Washington State, where recreational use is legal, in an effort to explore the prevalence of cannabis use disorder among both medical and nonmedical users,” revealed that “21 percent of people in the study had some degree of cannabis use disorder, which clinicians characterize broadly as problematic use of cannabis that leads to a variety of symptoms, such as recurrent social and occupational problems, indicating impairment and distress.”
       
According to CNN (8/29, LaMotte), “using both medical and recreational weed led to a more severe addiction than using medical marijuana alone, the study” concluded. This study’s findings mirror those “from other countries such as the Netherlands, Germany, Australia, New Zealand, Ireland and France.” In fact, “a 2020 meta-analysis of those countries and the US found 22% of cannabis users would develop a cannabis disorder during their lifetime – the risk rose to 33% for younger people who engaged in weekly or daily use of weed.”

Related Links:

— “Cannabis Use Disorder Is ‘Common’ Among Marijuana Users, Study Finds,”Matt Richtel, The New York Times, August 29, 2023

According to CNN (8/28, McPhillips, Christensen), researchers have found that “recurring gun injuries” are not uncommon. “About one of every 14 gunshot victims will be harmed by a firearm again within a year, according to” findings published online in the Annals of Internal Medicine. “Within five years, that risk rises to about one in eight, and it jumps to about one in six after eight years,” the study revealed.

Healio (8/28, Rhoades) reports, “Firearm injury survivors often experienced recurrent firearm injuries, particularly those who were young, uninsured, male and Black,” researchers concluded in an analysis that “included data from the St. Louis Region-Wide Hospital-Based Violence Intervention Program…repository on 10,293 adult and pediatric patients who presented with a firearm injury to a St. Louis level 1 trauma hospital from 2010 to 2019.” Of those patients, “9,553 survived the injury,” and “1,155 patients suffered a recurrent firearm injury.”

Related Links:

— “Shooting survivors have ‘distressingly high’ risk of repeat firearm injury, study finds, especially young Black males,”Deidre McPhillips and Jen Christensen, CNN, August 28, 2023

CNN (8/28, Musa) reports, “A new study from Boston University’s CTE Center has discovered more than 60 cases of chronic traumatic encephalopathy, known as CTE, in athletes who were under the age of 30 at the time of their death.” Additionally, the study “includes what researchers believe to be the first case of an American female athlete diagnosed with the disease.”
MedPage Today (8/28, George) reports, “Brain pathologies including chronic traumatic encephalopathy (CTE), a neurodegenerative disease, were identified in young deceased athletes, autopsy data” from “152 contact sports players under age 30 at the time of death” revealed. The study revealed that “CTE was diagnosed in 41.4%,” and “the mean age at death for players with evidence of autopsy-confirmed CTE was 25.” The findings were published online in JAMA Neurology.

Related Links:

— “Largest study of brains of athletes younger than 30 finds early signs of CTE even in amateur players,”Amanda Musa, CNN, August 28, 2023