Calls Growing For Greater Anxiety Screening Among Older Adults

The New York Times (2/26, Span) reports, “Anxiety is the most common mental health disorder; a 2017 study of older adults in six countries found that more than 17 percent had experienced an anxiety disorder within the past year.” And “recently, attention to anxiety has increased because of a draft recommendation from the United States Preventive Services Task Force” urging greater screening for anxiety among adults. One author of an “editorial on late-life anxiety in JAMA Psychiatry” said, “With a common disorder that causes a lot of impairment of quality of life and that has simple, inexpensive, straightforward kinds of treatment, I think screening is called for.”

Related Links:

— “Why Aren’t Doctors Screening Older Americans for Anxiety? “Paula Span, The New York Times, February 26, 2023

Inflammation In The Body May Trigger Or Exacerbate Depression In Brains Of Some Patients, Data Indicate

The Washington Post (2/23, J Sima) reports, “Inflammation in the body may be triggering or exacerbating depression in the brains of some patients,” with clinical data suggesting that “targeting and treating the inflammation may be a way to provide more-precise care.” According to the Post, “it appears that inflammatory agents in the blood can break down the barrier between the body and the brain, causing neuroinflammation and altering key neural circuits, researchers say,” and “in people at risk for depression, inflammation may be a trigger for the disorder.” The article goes on to summarize recent studies exploring how inflammation appears to be a “pathway to depression.”

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— “The Washington Post (requires login and subscription)

Unstable, Unsafe Living Situations And Intimate Partner Violence Increased Temporarily For Pregnant People In US During Pandemic, Analysis Finds

Healio (2/23, Welsh) reports that “during the first months of the COVID-19 pandemic, there was a temporary increase in unstable or unsafe living situations and intimate partner violence for pregnant people in the U.S., according to” results of a “cross-sectional population-based interrupted time-series analysis” published online in JAMA Network Open. The study team “noted a 38% increase in unstable and/or unsafe living situations during the first month of the COVID-19 pandemic…and a return to the overall trend afterward for the remaining study period,” as well as “a 101% increase in intimate partner violence during the first 2 months of the COVID-19 pandemic.”

Related Links:

— “Increase in domestic violence seen early in COVID-19 pandemic among pregnant individuals “Erin T. Welsh, Healio, February 23, 2023

Half Of Americans Say Government Should Prioritize Lowering Drug, Healthcare Costs, Poll Finds

The Hill (2/23, Hou) reports, “Half of Americans…say the government should emphasize lowering prescription drug costs and reducing the cost of health care over other public health-related priorities,” according to the Axios-Ipsos American Health Index. In “comparison, 14 percent” of poll respondents “listed reducing gun deaths and another 14 percent cited research into cures and treatment for major diseases as a top priority for government action.” The article adds, “Asked to identify what they believe is the No. 1 threat to public health in the U.S., 26 percent listed opioids and fentanyl, 21 percent listed obesity, 17 percent pointed to access to guns or firearms, and 12 percent cited cancer.”

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— “Americans worried about rising drug costs, health bills: survey “Chia-Yi Hou, The Hill, February 23, 2023

Patients With Trichotillomania And/Or Excoriation Disorder May Experience Symptom Improvements While Taking Memantine, Small Study Indicates

Psychiatric News (2/22) reports, “Patients with trichotillomania (also known as hair-pulling disorder) and/or excoriation (skin-picking) disorder may experience symptom improvements while taking the Alzheimer’s medication memantine,” investigators concluded in a study that “recruited 100 adults…with a current primary DSM-5 diagnosis of trichotillomania…excoriation disorder…or both.” The findings were published online Feb. 22 in the American Journal of Psychiatry, a publication of the American Psychiatric Association.

Related Links:

— “Memantine May Reduce Symptoms of Hair-Pulling, Skin-Picking Disorder, Psychiatric News, February 22, 2023

Pimavanserin May Be Most Effective Atypical Antipsychotic At Easing Parkinson’s Disease Psychosis While Sparing Motor Function, Systematic Review Indicates

Parkinson’s News Today (2/22, Maia) reports, “Among several atypical antipsychotics, Nuplazid (pimavanserin) seems to be the most effective at easing Parkinson’s disease psychosis…while sparing motor function,” researchers concluded in the findings of a 19-study systematic review and network meta-analysis that “evaluated outcomes with Nuplazid and other atypical antipsychotics such as clozapine, quetiapine, olanzapine, ziprasidone, and risperidone.” The findings were published online in the Journal of Geriatric Psychiatry & Neurology.

Related Links:

— “Nuplazid, clozapine treat Parkinson’s psychosis without motor decline “Margarida Maia, Parkinson’s News Today, February 22, 2023

Being, Remaining Physically Active Throughout Adulthood Tied To Higher Cognition At Age 69, Data Indicate

MedPage Today (2/21, George) reports, “Being and remaining physically active throughout adulthood was linked with higher cognition at age 69,” researchers concluded in a study that “followed 1,417 participants in the 1946 British Birth Cohort, a long-running U.K. study of people born the same week in 1946.” The study revealed that “effect sizes were similar across all adult ages, suggesting that being physically active at any time in adulthood – even as little as once a month – was tied to higher cognition.” The findings were published online in the Journal of Neurology, Neurosurgery, and Psychiatry.

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FDA Committees Vote Unanimously To Recommend Approval For OTC Naloxone

Psychiatric News (2/21) reports that last week, the FDA ‘s “Nonprescription Drugs Advisory Committee and the Anesthetic and Analgesic Drug Products Advisory Committee voted unanimously, 19-0, to recommend that Narcan (naloxone HCl) 4 mg nasal spray be made available without a prescription, Emergent BioSolutions announced” in a Feb. 15 press release. Naloxone “reverses an opioid overdose by blocking the effects of opioids.” While the agency “is not bound by the committees’ guidance,” it “will take their advice into consideration when it makes its decision on whether to make the drug available over the counter (OTC).” The approval decision is “expected by March 29.”

Related Links:

— “FDA Advisory Panel Recommends Approval for Over-the-Counter Narcan, Psychiatric News, February 21, 2023

Dementia incidence rates fall, but neurodegenerative pathologies show few differences over time

MedPage Today (2/20, George) reports, “Neurodegenerative pathologies have shown few differences over time despite falling dementia incidence rates,” investigators concluded after examining “brain autopsy data” from “over 1,500 deceased people from birth epochs spanning 25 years (1905-1930).” The study also revealed, however, that “brain atherosclerosis and arteriosclerosis were dramatically lower over the years.” The findingswere published online in JAMA Neurology.

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Systematic Review Reveals 22% Of Children, Adolescents Appear To Exhibit Disordered Eating

According to Healio (2/20, Weldon), the findings of a 32-study “systematic review and meta-analysis” published online Feb. 20 in JAMA Pediatrics revealed that “22% of children and adolescents exhibit disordered eating.” The 32 studies encompassed “63,181 participants from 16 countries.”

Related Links:

— “‘Incredibly high’ proportion of children exhibit disordered eating behaviors “Rose Weldon, Healio , February 20, 2023