Alopecia Areata Associated With Increased Risk Of Developing Psychiatric Disorders, Study Suggests

Dermatology Advisor (12/19, Stong) reported a study found that “alopecia areata is associated with a significantly increased risk of developing psychiatric disorders.” The research team observed the “alopecia group had a cumulative incidence of any psychiatric disorder of 17.3% compared with 3.9% in the control group, for a risk ratio (RR) of 4.49. Severe psychiatric illnesses such as schizophrenia and bipolar disorder were diagnosed in 0.7% of patients in the alopecia group and 0.2% of patients in the control group. Specifically, 6.4% of patients with alopecia had a depressive disorder compared with 1.3% of control patients. Anxiety disorders occurred in 10.6% of the alopecia group and 2.8% of the control group.” Additionally, “women with alopecia had an increased psychiatric burden compared with men.” The study was published in Dermatology and Therapy.

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— “Alopecia Areata Is Associated With Increased Risk for Psychiatric Disorders,”Colby Stong, Dermatology Advisor, December 19, 2025

Study Suggests Different Psychiatric Conditions May Be Driven By Similar Genetics

HealthDay (12/19, Thompson) reported a study suggests that “psychiatric conditions as varied as schizophrenia and bipolar disorder might be driven by very similar genetic underpinnings.” According to researchers, “mental health problems can be sorted into five general genetic categories, each with a shared ‘genetic architecture’ driving people’s illness.” The five general categories involving 238 genetic variants includes: disorders with “compulsive features” like anorexia, Tourette disorder and obsessive-compulsive disorder; “internalizing” disorders like depression, anxiety and post-traumatic stress disorder; substance use disorders; neurodevelopmental conditions “like autism and attention deficit/hyperactivity disorder;” and bipolar disorder and schizophrenia. With that said, “70% of the genetic signal associated with schizophrenia is also associated with bipolar disorder, the study said.” The study was published in Nature.

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— “Different Mental Health Conditions Share Similar Genetics, Study Says,”Dennis Thompson, HealthDay, December 19, 2025

Nicotine is toxic to heart, blood vessels regardless of how it is consumed, report says

HealthDay (12/18, Thompson) reports, “It’s beside the point to debate whether vaping or nicotine pouches can be more healthy than smoking a cigarette, a major new report argues.” HealthDay says “nicotine is toxic to the heart and blood vessels regardless of how it’s consumed, according to an expert consensus report.” One researcher said, “Across cigarettes, vapes, heated tobacco and nicotine pouches, we consistently see increased blood pressure, damage to blood vessels and a higher risk of heart disease. … No product that delivers nicotine is safe for the heart.” The findings were published in the European Heart Journal.

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— “Vapes Or Cigs, Doesn’t Matter — Nicotine Is Toxic To Heart Health, Experts Say,”Dennis Thompson, HealthDay , December 18, 2025

President Signs Executive Order To Reclassify Marijuana As Less Dangerous Drug

The AP (12/18, Whitehurst, Barrow) reports the President signed an executive order Thursday that could reclassify “marijuana away from its current classification as a Schedule I drug, alongside heroin and LSD,” and instead would be “a Schedule III substance, like ketamine and some anabolic steroids.” While the reclassification by the Drug Enforcement Administration would not make cannabis legal for recreational use by adults nationwide, “it could change how the drug is regulated and reduce a hefty tax burden on the cannabis industry.” Furthermore, it will also “open new avenues for medical research,” and overall represents “a major shift in federal drug policy that inches closer to what many states have done.”

NBC News (12/18, Gregorian, Reichman, Dean) reports the order “directs Attorney General Pam Bondi to conclude the formal rescheduling process, which has been going on for more than a year, and move to publish a final rule that would reclassify cannabis.” It also “directs the White House deputy chief of staff for legislative, political and public affairs to work with Congress to allow people in the U.S. to benefit from access to CBD products while still restricting sale and access to products that pose serious health risks.”

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— “Trump signs executive order that could reclassify marijuana as a less dangerous drug,”Lindsay Whitehurst and Bill Barrow , AP, December 18, 2025

Single Half-Hour Course Can Help Young Adults Feel Less Anxious, Depressed For Up To A Month, Study Suggests but wanes after 3 Months

HealthDay (12/18, Thompson) reports a study found that a single half-hour course could help young adults “feel less anxious and depressed, by helping them increase their tolerance of uncertainty.” According to researchers, “young adults who took the course titled ‘Uncertainty-Mindset Training’ continued to feel better a month after taking it.” Even though the course “lasted less than a half-hour,” participants, up to a month later, still “showed substantial improvement in their ability to tolerate uncertainty, as well as decreases in anxiety and depression.” Researchers noted that “three months later, these participants’ tolerance of uncertainty was still much improved, but the reductions in depression and anxiety had started to wane.” The study was published in Psychological Medicine.

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— “Anxious, Depressed About An Uncertain World? Training Can Help You Cope, Study Says,”Dennis Thompson, HealthDay , December 18, 2025

Public Health, National Security Experts Skeptical About Administration’s Declaration Of Fentanyl As A Weapon Of Mass Destruction

The Washington Post (12/16, Ovalle) reports some policy and health experts say the President’s recent declaration “that illicit fentanyl is a weapon of mass destruction” is “a stretch,” adding that “the move may have little practical impact on curbing drug supply, addiction and overdose deaths.” The Administration “has cited the deadly drug crisis in enacting tariffs on China and Mexico, labeling criminal groups terrorist organizations and launching military strikes on suspected smuggling drug boats in the Caribbean and Eastern Pacific.” Experts in national security and transnational crime “say such heavy handed measures could harm global alliances needed to combat traffickers.” Public health experts “say the designation may also exaggerate fears about fentanyl.”

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— “The Washington Post (requires login and subscription)

Study Finds Women Physicians, Early-Career Physicians Face Higher Social Isolation, Correlating With Increased Burnout And Suicidal Ideation

Medical Economics (12/16, Payerchin) reports “a national study found” that women physicians “and early-career physicians face higher social isolation, correlating with increased burnout and suicidal ideation.” Investigators found that “specialties like pathology, emergency medicine, and settings like veterans’ hospitals report the highest isolation levels.” The researchers said, “Physicians have the same innate need for connection as all other human beings. … Efforts by both organizations and physicians to prioritize and nurture personal and professional relationships and social connections may enhance well-being and physicians’ ability to care for others.” The findings were published in Mayo Clinic Proceedings.

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— “Social isolation contributes to physician feelings of burnout, workplace satisfaction, suicidal ideation,”Richard Payerchin, Medical Economics, December 16, 2025

Body Dissatisfaction May Increase Risk Of Eating Disorders, Depressive Symptoms, Study Finds

HealthDay (12/17, Gotkine) reports a study found that “body dissatisfaction may causally increase eating disorder and depressive symptoms.” The investigators utilized “data from the Twins Early Development Study to examine the longitudinal associations between body dissatisfaction at age 16 years and later eating disorder and depressive symptoms, as well as body mass index (BMI), in young adulthood.” The researchers “observed an association for a 1-point increase in body dissatisfaction with a 1.99-point higher eating disorder symptom score, a 0.59-point higher depressive symptom score, and a 0.27 kg/m2 higher BMI, on average. Higher body dissatisfaction was also associated with more severe eating disorder and depressive symptoms in monozygotic and dizygotic twin difference analyses.” They noted that “the association was smaller for BMI and was less precisely estimated in monozygotic twins.” The study was published in The Lancet Psychiatry.

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— “Body Dissatisfaction Linked to Eating Disorder, Depressive Symptoms,”Elana Gotkine, HealthDay , December 17, 2025

Survey Finds Teen Use Of Alcohol, Nicotine And Marijuana Remains At Record Lows

The AP (12/17, Stobbe) reports “teen use of alcohol, nicotine and marijuana remains at record lows, according to” the results (PDF) of the Monitoring the Future survey that were released Wednesday. Teenagers “consume a lot of energy drinks, though. And there are slight, but concerning, increases in heroin and cocaine use.” However, “the findings indicate teens are drinking, smoking and using substances at much lower rates than in the past.” About “two-thirds of 12th graders this year said they hadn’t used alcohol, marijuana, cigarettes or electronic cigarettes in the previous 30 days.” Thirty years ago, “the figure was closer to about one-third.” The new “findings also seem to echo other surveys that show continued declines in teen sexual activity, which experts say is at least partly due to teens connecting through smartphones and social media instead of in person.”

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— “Teen drug use remains low, but survey finds small rise in heroin and cocaine use,”Mike Stobbe , AP, December 17, 2025

Six Midlife Depression Symptoms Linked To Higher Dementia Risk, Study Suggests

MedPage Today (12/15, George) reports a study found that “six midlife symptoms of depression were tied to an increased risk of dementia.” Results show that “depressive symptoms that emerged as midlife indicators of increased dementia risk” include: losing confidence in oneself; not able to face up to problems; not feeling warmth and affection for others; feeling nervous and strung-up all the time; not satisfied with the way tasks are carried out; and difficulty concentrating. Researchers noted “these associations were independent of established dementia risk factors like APOE4 status, cardiometabolic conditions, and lifestyle factors.” The study was published in The Lancet Psychiatry.

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