Autism Appears To Arise From Brain Changes Located Throughout Cerebral Cortex, Not Just In Specific Areas, Small Postmortem Study Reveals

HealthDay (11/3, Thompson) reports, “Autism is a more comprehensive disorder than previously thought, and appears to arise from brain changes located throughout the cerebral cortex, not just in specific areas,” researchers concluded after examining “the genetics in 11 cortical regions by sequencing RNA from brain tissue samples gathered from 112 people after death,” then comparing “what they found to the genetics of healthy brain tissue.” The findings were published online Nov. 2 in the journal Nature.

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— “Autism Alters Brain in Major Ways, Study Finds “Dennis Thompson, HealthDay, November 3, 2022

Mania Tied To Reduced Dopamine Transporter Density Levels Among People With Bipolar Disorder, Small Scan Study Suggests

Healio (11/3, Downey) reports, “Mania was associated with reduced dopamine transporter density levels among those with bipolar disorder,” investigators concluded in a scan study that included 47 participants, 26 of whom had bipolar disorder and “21 matched healthy controls.” The findings were published online Nov. 2 in JAMA Psychiatry.

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— “Mania associated with lower dopamine transporter density in bipolar patients “Ken Downey Jr., Healio, November 3, 2022

Stroke risk appears to increase for young adults who are moderate-to-heavy drinkers

MedPage Today (11/2, George) reports, “People in their 20s and 30s who were moderate-to-heavy drinkers were more likely to have a stroke in early adulthood compared with those who consumed low amounts of alcohol each week,” researchers concluded in study findings published online in the journal Neurology. The study of 1,536,668 young people revealed that those “who consumed 105 g of alcohol per week, or 15 g per day, for two or more years were more likely to have a stroke over 5.6 years of follow-up versus light drinkers,” and “stroke risk rose as the number of years of moderate-to-heavy drinking in young adulthood increased.”

HealthDay (11/2) reports the study also found that “high alcohol burden scores were associated with significantly higher risks for hemorrhagic stroke.”

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Youth Who Survive Firearm Injury Significantly More Likely To Access Mental Health Services Within One Year Of Injury Than Children Without A Firearm Injury, Data Indicate

Psychiatric News (11/2) reports, “Youth who survive a firearm injury are significantly more likely to access mental health services – including services for substance use disorders – within one year of the injury than are children who do not have a firearm injury,” investigators concluded in a study that “used commercial insurance and Medicaid claims databases to examine use of mental health and substance use treatment among 2,127 children and adolescents (average age 13.5 years) who sustained firearm injuries between January 2016 and the end of December 2017, and an equal number of age-matched youth who had not had a firearm injury.” The findings were published online Nov. 2 in JAMA Surgery.

Related Links:

— “Youth More Likely to Access Mental Health, Substance Use Treatment Following a Firearm Injury, Psychiatric News, November 2, 2022

Bill Seeks To Make Online Assistance Of Suicide A Federal Crime

According to the New York Times (11/2, Dance, Twohey), legislators “are seeking to make online assistance of suicide a federal crime, pushing to hold accountable both individual users and the tech companies and websites that allow such content on their platforms.” A bipartisan measure “introduced in the House of Representatives on Monday, the Stop Online Suicide Assistance Forums Act, comes amid rising concern over suicide rates among young people, and mounting evidence of online dangers.” This proposed legislation “would allow prosecution under an existing exception to Section 230 of the Communications Decency Act, the law that governs online activity and typically shields website operators from liability for content posted by users.”

Related Links:

— “Bill Outlawing Online Suicide Assistance Would Open Sites to Liability ” Gabriel J.X. Dance and Megan Twohey, The New York Times, November 2, 2022

Women Who Begin Taking Oral Or Transdermal Estrogen Or Estrogen/Progestin For Menopause Between Ages Of 45 And 50 May Be At Greater Risk Of Developing Depression, Study Indicates

Psychiatric News (11/1) reports, “Women who begin taking oral or transdermal estrogen or estrogen/progestin for menopause between the ages of 45 and 50 appear to be at greater risk of developing depression,” investigators concluded in a study that “included 825,238 women in Denmark who turned 45 years between 1995 and the end of 2017.” The findings were published online Nov. 1 in JAMA Network Open.

Related Links:

— “Oral, Transdermal Hormone Therapy for Menopause Before Age 50 May Increase Risk of Depression, Psychiatric News , November 1, 2022

Estimated One In Eight Deaths Of People In US Ages 20 To 64 Attributable To Excessive Alcohol Use In 2015-2019, Study Finds

The New York Times (11/1, Alcorn) reports, “An estimated one in eight deaths of Americans ages 20 to 64 in the years 2015-19 was the result of injuries or illness caused by excessive alcohol use, according to a” study that “assessed the effects of alcohol on people of working age, who accounted for nearly two-thirds of the country’s annual average of 140,000 alcohol-related deaths.” The study showed that “among those ages 20 to 49, one in five deaths was attributable to drinking, and for those ages 20 to 34, it was one in four.” The findings were published online in JAMA Network Open.

MedPage Today (11/1, Hamza) reports alcohol-attributed deaths “were more common among men than women (15% vs 9.4%), the authors wrote.”

CNN (11/1, Holcombe) also reports.

Related Links:

— “Alcohol Deaths Claim Lives of Working-Age Americans “Ted Alcorn, The New York Times, November 1, 2022

Telehealth Use Remains High Among Young Adults And For Primary Care, Mental Health Services, Survey Reveals

mHealth Intelligence (10/31, Melchionna) reports “that although in-person care is the preferred channel of care, telehealth use remains highly used among young adults and those engaging in primary care and mental health services,” according to a survey by Stericycle Communication Solutions in collaboration with Ipsos. In comparison, the “survey of 1,004 adults” found that “patients do not prefer virtual visits for specialties such as dermatology, pediatrics, ENT, cardiology, urology, gynecology, orthopedics, and pulmonology.”

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— “Patients Prefer Telehealth for Primary Care, Mental Health Needs ” Mark Melchionna, mHealth Intelligence, October 31, 2022

Naltrexone May Significantly Reduce Binge Drinking Among Sexual And Gender Minority Men With Mild Or Moderate Alcohol Use Disorder, Small Study Suggests

Psychiatric News (10/31) reports, “Naltrexone may significantly reduce binge drinking among sexual and gender minority men (men who have sex with men) with mild or moderate alcohol use disorder,” investigators concluded in a 12-week study that “involved 120 sexual and gender minority men (one transgender male and 119 cisgender males) who reported at least one binge-drinking episode (five or more drinks on a single occasion) per week in the past three months, but who did not meet DSM-IV criteria for alcohol dependence.” The findings were published online Oct. 26 in the American Journal of Psychiatry, a publication of the American Psychiatric Association.

Related Links:

— “Naltrexone May Reduce Binge Drinking in Sexual and Gender Minority Men, Psychiatric News, October 31, 2022

Children, Adolescents Who Experience Migraines May Be More Likely To Have Anxiety, Depression Than Their Peers Without Migraines, Systematic Review Suggests

MedPage Today (10/31, DePeau-Wilson) reports, “Children and adolescents who experience migraines are more likely to have anxiety and depression compared with those who don’t have migraines,” researchers concluded in a 51-study systematic review and meta-analysis, the findings of which were published online Oct. 31 in JAMA Pediatrics.

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