Up To Two Thirds Of Women In Perimenopause Report Cognitive Problems, Researchers Say

The Washington Post (5/14, Cimons) reported, “The Department of Health and Human Services’ Office on Women’s Health says up to two-thirds of women in perimenopause report cognitive problems, although estimates as to the extent of affected women differ among experts.” It’s also “still unclear what causes these deficits – hormones or other factors – and whether they continue postmenopause.” One recent study “of low-income women of color, some of them HIV infected, suggests that cognitive declines may linger into postmenopause for some, although demographics also may influence this, says Stephanie Faubion, medical director of the North American Menopause Society (NAMS), which published the research in its journal, Menopause.” Peter Schmidt, “chief of the behavioral endocrinology branch at the National Institute of Mental Health and one of the study authors, says: ‘I think it’s very clear that a subgroup of women do develop depression, for some for the first time in their lives, and there is evidence that declining estrogen contributes to its development.’”

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— “The Washington Post (requires login and subscription)

Entorhinal Hypometabolism Identified On Fluorodeoxyglucose PET Scans Serve As “Strong And Independent Predictor” Of Future Cognitive Decline In Patients With Preclinical Alzheimer’s Disease, Study Indicates

Healio (5/13, Ernst) reports researchers found “entorhinal hypometabolism identified on fluorodeoxyglucose PET scans served as a ‘strong and independent predictor’ of future cognitive decline in” patients with preclinical Alzheimer’s disease. The findings were published in Neurology.

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— “Entorhinal hypometabolism on PET scan predicts cognitive decline in preclinical AD “Julia Ernst, Healio, May 13, 2021

Patients With Opioid Dependence Who Received Subcutaneous Buprenorphine Report Higher Satisfaction And Lower Treatment Burden Compared To Those Who Received Sublingual Buprenorphine, Study Indicates

Healio (5/13, Gramigna) reports researchers found in a randomized clinical trial that “patients with opioid dependence who received subcutaneous buprenorphine reported higher satisfaction and lower treatment burden vs. those who took sublingual buprenorphine.” The findings were published in JAMA Network Open.

Psychiatric News (5/13) reports the study’s “results highlight the importance of using patient-reported outcomes when developing medication treatment for substance use disorders.”

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— “Patients report subcutaneous buprenorphine preferable to sublingual formulation “Madison Weller, Healio, May 13, 2021

Borderline Personality Disorder Diagnosis And Related Criteria Of Self-Injurious Behaviors And Chronic Emptiness Significantly Increased Suicide Attempt Risk, Study Indicates

Healio (5/13, Gramigna) reports researchers conducted a cross-sectional study and found that “borderline personality disorder diagnosis and related criteria of self-injurious behaviors and chronic emptiness significantly increased suicide attempt risk.” The findings were published in JAMA Network Open.

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— “Self-injurious behaviors, chronic emptiness increase suicide attempt risk in BPD “Joe Gramigna, Healio, May 13, 2021

Declining Kidney Function May Be Strongly Associated With Development Of Dementia Among Senior Adults, Study Indicates

Renal & Urology News (5/12, Schieszer) reports, “Declining kidney function appears to be strongly associated with the development of dementia among patients aged 65 years or older,” investigators concluded after analyzing “the association of estimated glomerular filtration rate (eGFR) with the risk of dementia among 329,822 residents in Stockholm accessing health care between 2006 and 2011.” Study participants “were aged 65 years or older, had no history of dementia, and had not received renal replacement therapy.” The findings were published online in the journal Neurology.

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— “Renal Function Decline Associated With Increased Dementia Risk “John Schieszer, Renal & Urology News, May 12, 2021

Certain Medications May Inadvertently Raise A Person’s Blood Pressure, Researchers Say

Cardiovascular Business (5/12, Walter) reports, “Antidepressants, nonsteroidal anti-inflammatory drugs (NSAIDs) and oral steroids are just some of the medications that could inadvertently raise a person’s blood pressure,” investigators concluded after tracking “data from more than 27,000 participants who responded to the National Health and Nutrition Examination Survey from 2009 to 2018.” The findings are slated for presentation at ACC.21, the American College of Cardiology’s 70th annual scientific session.

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— “Antidepressants, other common medications linked to high blood pressure “Michael Walter, Cardiovascular Business, May 12, 2021

Long-Term Use Of Prescription Sleep Medications May Not Help Women With Chronic Sleep Problems, Research Suggests

NBC News (5/11, Carroll) reports research published in BMJ Open indicates that “prescription sleep medications can help women struggling with occasional insomnia but probably won’t help with chronic sleep problems.” The study, using “two years of data from nearly 700 middle-age women,” found “that long-term use of medications such as Ambien [zolpidem], Lunestra [eszopiclone] or some anti-anxiety prescriptions didn’t help women sleep better in the long run compared to women who didn’t use prescription pills.”

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— “Prescription sleep pills not likely to help women in the long run, study finds “Linda Carroll, NBC News, May 11, 2021

Hospitalizations For Abusive Head Trauma In Children Younger Than Age 5 Declined During The COVID-19 Pandemic, Study Indicates

Healio (5/11, Downey) reports researchers found “there was a significant decline in hospitalizations for abusive head trauma among children aged younger than 5 years during the COVID-19 pandemic.” The findings were published in Pediatrics.

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— “Pediatric hospitalizations for abusive head trauma decline during pandemic “Ken Downey Jr., Healio11, May , 2021