More evidence highlights health hazards of vaping

The New York Times (7/9, Blum) reports a recent study published in ACS Central Science found that the mist from popular vapes contains “such high levels of heavy metals that one researcher thought their machine had malfunctioned.” This follows other studies suggesting “vaping can affect the heart, lungs and brain.” Experts told The Times that “the liquids in e-cigarettes can release known carcinogens, like formaldehyde and acetaldehyde, when heated. These and other chemicals can damage blood vessels, drive inflammation and contribute to cardiovascular disease risk.” Vaping can also lead to chronic inflammation in the airways and lungs, as well as exacerbating asthma and COPD symptoms. Research has also shown that “e-cigarettes are addictive. Dependence can be especially problematic for adolescents, whose brains are developing.”

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Review Questions Severity Of Withdrawal After Discontinuing Antidepressants

The New York Times (7/9, Barry) reports a systemic review and meta-analysis “found that a week after quitting antidepressants, patients reported symptoms like dizziness, nausea and vertigo,” but they mostly remained “below the threshold for clinically significant” withdrawal. Researchers criticized a 2019 UK study “that found that 56 percent of patients suffered from withdrawal symptoms” after discontinuing antidepressants for including “data from online surveys as a quantitative measure, for failing to control for the placebo effect, and for failing to distinguish between various types of antidepressants.” The new review, “based on 50 studies with more than 17,000 subjects,” found that “patients who had quit antidepressants were 5.5 times as likely to report dizziness, 6.4 times as likely to report vertigo and 3.1 times as likely to report nausea compared to placebo. But on average, the number of withdrawal symptoms had risen modestly, by only one compared with placebo, which is not considered clinically significant.” The review was published in JAMA Psychiatry.

Psychiatric News (7/9) adds that “antidepressant discontinuation was not associated with greater depressive symptoms in the first two weeks compared with placebo, despite being measured in studies specifically examining major depressive disorder; this suggests that later presentation of depression symptoms is more likely to represent depression relapse, researchers wrote.”

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Adolescents Who Died By Firearm Suicide More Likely To Have Lived In Households With Unlocked Firearms, Study Finds

MedPage Today (7/8, Firth) reports a study found that “the odds of dying by firearm suicide were substantially lower for teens ages 15 to 20, but not for adults, when all firearms at home were locked.” In a study of 725 people who died by suicide, 83.6% died by firearms. Researchers observed that “adults who died by firearm suicide were no more likely than those who died by other suicide methods to have lived in a home with locked firearms or unloaded firearms.” However, “of decedents ages 15 to 20 years – classified as adolescents in this study – 26 of 43 (60.3%) who died by firearm suicide had lived in a home with unlocked firearms, but none of the seven adolescents who died by non-firearm suicide did.” Furthermore, “among adolescents living in homes in which all firearms were locked, the suicide method was not tied to whether any firearm was unloaded.” The studywas published in JAMA Network Open.

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Low-dose CBD use linked to liver injury in some people

NBC News (7/7, Cox) reports a study from the FDA’s Division of Applied Regulatory Science “suggests there are still ongoing questions about the safety of even low doses of cannabidiol, even as CBD capsules, gummies, edibles, oils and lotions have become increasingly omnipresent in the United States in recent years.” The researchers “carried out a randomized double-blind placebo-controlled trial last year to assess how low-dose CBD affects liver function in a group of healthy middle-aged men and women.” They observed that 5% of participants “showed greatly elevated levels of the liver enzyme aminotransferase, a known marker of liver cell damage or inflammation.” Additionally, “women appeared to be more vulnerable than men. The liver enzyme returned to normal within one or two weeks of stopping CBD.” The study was published in JAMA Internal Medicine.

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— “Even low doses of CBD may cause harm to the liver in some people, FDA study finds,” David Cox, NBC News, July 7, 2025

US Children Have Become Increasingly Unhealthy Over Past Two Decades, Study Shows

The AP (7/7, Ungar , Aleccia ) reports a new study published in JAMA shows that the health of children “has deteriorated over the past 17 years, with kids today more likely to have obesity, chronic diseases and mental health problems like depression.” The research team “analyzed surveys, electronic health records from 10 pediatric health systems and international mortality statistics.” They found that “obesity rates for U.S. children 2-19 years old rose from 17% in 2007-2008 to about 21% in 2021-2023.” In addition, a US “child in 2023 was 15% to 20% more likely than a U.S. child in 2011 to have a chronic condition such as anxiety, depression or sleep apnea.” Furthermore, US children “were around 1.8 times more likely to die than kids in other high-income countries from 2007-2022,” with firearm-related incidents and motor vehicle crashes “much more common” in contrast to children of the same age in other countries.

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— “American kids have become increasingly unhealthy over nearly two decades, new study finds,”Laura Ungar and Jonel Aleccia , AP, July 7, 2025

988 Lifeline Sees Higher Volume Three Years After Launch, But Option For LGBTQ Youth Recently Cut

ABC News (7/4, Livingston, Cunningham) reported that “three years after the launch of the three-digit 988 Suicide & Crisis Lifeline, the service is seeing increases in call volume, state-level support and reported effectiveness, as well as reductions in specialized offerings, including one designed to help LGBTQ youth.” Since launching in July 2022, “the Lifeline has answered over 13 million calls, chats and texts across the U.S. and its territories, according to SAMHSA.” Dr. John Palmieri, acting director of SAMHSA’s 988 Lifeline Office, told ABC News there has been “about a 20% higher volume of calls, texts and chats” this year compared to the year prior. However, the Trump Administration “has implemented significant workforce reductions for HHS and SAMHSA over the last few months.” Notably, SAMHSA “recently announced that the Press 3 option, which provides specialized care for LGBTQ youth, will no longer be a part of the Lifeline.”

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— “3 years later, 988 Lifeline sees higher volume but special option for LGBTQ youth cut,”Kelly Livingston, ABC News, July 4, 2025

Black Patients Less Likely To Receive Outpatient Treatment Referrals After Suspected Opioid Overdose, Study Finds

MedPage Today (7/2, Firth) reports a study found that “referrals for outpatient treatment after a suspected opioid overdose ranged from 8% to 44%, and Black patients were less likely to receive such a referral versus white patients.” Researchers observed that “among nearly 1,700 emergency department (ED) patients with suspected opioid overdose, 17.8% received a referral for outpatient treatment, 42.4% received a naloxone kit or prescription, and 8.4% received a buprenorphine prescription.” Yet, they noted that just “5.7% of Black patients received an outpatient treatment referral versus 9.6% of white patients.” Researchers concluded, “These findings underscore the need for targeted interventions to address racial disparities in ED care for [opioid use disorder], particularly in enhancing referral processes and buprenorphine prescribing practices for Black patients.” The study was published in JAMA Network Open.

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ADHD Medications Remain Associated With Reduced Risk For Real-World Adverse Outcomes, Study Finds

HealthDay (7/2, Gotkine) reports a study found that “attention-deficit/hyperactivity disorder (ADHD) medications remain associated with a reduced risk for various real-world outcomes, but the magnitude of these associations decreases alongside increasing prescription rates.” The researchers observed that “across age groups and sexes and over time, ADHD medication was consistently associated with lower risks for self-harm, unintentional injury, traffic crashes, and crime.” They noted that “as prescription rates increased, the associations between ADHD medication use and lower risks for unintentional injury, traffic crashes, and crime appeared to weaken. The weakening trend for unintentional injury and traffic crashes was not fully explained by changes in age and sex distribution of individuals receiving ADHD medication.” The study was published in JAMA Psychiatry.

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— “ADHD Medications Remain Linked to Lower Risk for Real-World Adverse Outcomes,”
Elana Gotkine , HealthDay , July 2, 2025

[Democratic] States File Lawsuit Against Administration’s School Mental Health Funding Cuts

The Hill (7/1, Lonas ) reports 16 [Democratic-led] states “filed a lawsuit against the Trump administration Monday challenging the Department of Education’s cuts to mental health funding for schools.” The Education Department in April “announced the $1 billion cut to mental health funding, citing concerns with diversity, equity and inclusion (DEI) initiatives embedded in the contracts.” The states argue that the “contracts were unlawfully terminated under the Administrative Procedure Act and that the cancellation goes against congressional mandates.” The lawsuit maintains the cuts would cause “immediate and devastating harm” to schools.

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— “Democratic states sue Trump administration over school mental health funding cuts,” Lexi Lonas Cochran , The Hill, July 1, 2025

Patients With Opioid Use Disorder Covered By Medicaid, Medicare Less Likely To Receive Adequate Addiction Treatment, Study Finds

HealthDay (7/1, Thompson ) reports a study found that people with opioid use disorder “covered by Medicare and Medicaid are less likely to receive the mental health and substance use treatment that they need.” In contrast, people with opioid use disorder who have “public insurance receive more than twice as many sessions if their therapy is also covered by other sources, such as court-mandated treatment.” Overall, researchers observed that patients diagnosed with opioid use disorder “were more likely to get all the help they needed if they had additional coverage on top of Medicaid or Medicare.” Study authors commented, “It’s the exact opposite of how we should be helping people.” The study was published in
Addiction Science & Clinical Practice.

Related Links:

— “Medicaid, Medicare Don’t Adequately Cover Addiction Treatment, Study Says,”
Dennis Thompson , HealthDay , July 1, 2025