HCP Live (1/24, Brooks) reports, “The clinical impact of treatment interventions for mood may span beyond mental health, according to findings from a recent systematic review and meta-analysis.” The research “showed treatments addressing mood outcomes also demonstrated beneficial effects for general inflammation and inflammatory bowel disease (IBD)-specific biomarkers, further detailing the greater impact of psychological interventions for accentuating the effect on biomarkers and objective disease outcomes.” The findings were published in eBiomedicine.

Related Links:

— “Mental Health Interventions Reduce Inflammatory Biomarkers in IBD by 18%,” Abigail Brooks, MA, HCP Live, January 24, 2024

Healio (1/23, Hornick) reports, “Individuals using nicotine e-cigarettes have a higher likelihood of quitting smoking compared with nicotine replacement therapy users, according to” research. The findings were published in Cochrane Database of Systematic Reviews.

Related Links:

— “E-cigarette use vs. nicotine replacement therapy leads to higher quit rates,” Isabella Hornick, Healio, January23 , 2024

HCP Live (1/23, Derman) reports, “Anxiety and depression symptoms increased in trigger states (states where Dobbs triggered a pre-existing ban on abortion) following the Dobbs abortion decision overturning Roe vs. Wade and Planned Parenthood v. Casey, according to a new study” published in JAMA Open Network. In the study, researchers “compared changes in symptoms in the 13 trigger states (159, 854 respondents) and the 37 non-trigger states (558,899 respondents).” They found “respondents in trigger states had a mean PHQ-4 of 3.51 which increased to a score of 3.81 post-Dobbs decision. Moreover, the team observed a significantly greater increase in the mean Patient Health Questionnaire-4 in trigger states versus non-trigger.”

Related Links:

— “Anxiety, Depression Symptoms Increase Post-Dobbs Abortion Decision,” Chelsie Derman, , January 23, 2024

ABC News (1/22, Hannon) reports, “Injuries, overtraining and burnout are contributing to a high dropout rate in youth sports, according to a new report from the nation’s leading group of pediatric doctors.” The report from the American Academy of Pediatrics “found that 70% of kids drop out of organized youth sports by age 13.” Additionally, “nearly 1 in 10 youth athletes experience burnout, and as many as 35% experience overtraining, according to the report.”

Related Links:

— “Leading pediatric group warns competitive youth sports are leading to burnout, injuries,” Dr. Erin Hannon, ABC News, January 22, 2024

MedPage Today (1/22, Robertson ) reports, “The risk of congenital malformations appears to be lower with buprenorphine than with methadone when taken during the first trimester of pregnancy for opioid use disorder (OUD), according to an analysis of Medicaid data.” In the study, published in JAMA Internal Medicine, “in the buprenorphine group, risk of congenital malformations was 50.9 out of 1,000 pregnancies compared with 60.6 per 1,000 in the methadone group.”

Related Links:

— MedPage Today (requires login and subscription)

CNN (1/22, Howard ) reports, “Testing a person’s blood for a type of protein called phosphorylated tau, or p-tau, could be used to screen for Alzheimer’s disease with ‘high accuracy,’ even before symptoms begin to show, a new study suggests.” The research “involved testing blood for a key biomarker of Alzheimer’s called p-tau217, which increases at the same time as other damaging proteins — beta amyloid and tau — build up in the brains of people with the disease.” The “simple blood test was found to be up to 96% accurate in identifying elevated levels of beta amyloid and up to 97% accurate in identifying tau.” The findings were published in JAMA Neurology.

The Hill (1/22, Sforza ) also covers the story.

Related Links:

— “New blood test that screens for Alzheimer’s may be a step closer to reality, study suggests,” Jacqueline Howard, CNN, January 22, 2024

HCP Live (1/22, Derman) reports, “In a new study, older adults with treatment-resistant schizophrenia reported significantly fewer adverse events of clozapine than young adults.” Investigators “obtained data from a retrospective cohort study in a large psychiatric institute in the Netherlands, including 284 participants diagnosed with treatment-resistant schizophrenia who started taking clozapine between 2011 and 2020,” and “compared the number and type of adverse events, as well as the number of treatment discontinuations and the time until discontinuation due to adverse events, of older adults versus younger adults.” The findings were published in the International Journal of Geriatric Psychiatry.

Related Links:

— “Young Adults at Greater Risk of Adverse Events with Clozapine than Older Adults,” Chelsie Derman, HCP Live, January 22, 2024

HCP Live (1/20, Derman) reported, “In addition to the increased risk of fracture, a new study suggests osteoporosis could put older adults at an increased risk of depression.” Investigators found that “individuals with osteoporosis had a 73% greater risk of experiencing depression symptoms than individuals without osteoporosis.” The findings were published in Public Health.

Related Links:

— “Osteoporosis Could Signal Increased Risk of Depression in Older Adults,” Chelsie Derman, HCP Live, January 20, 2024

HealthDay (1/19, Thompson ) reported, “People coming off antidepressants often struggle with emotional and social turmoil, especially if they quit their meds cold turkey, a new study” indicated. The study, in which investigators “conducted interviews with 20 people who had attempted within the past year to withdraw from SSRI…antidepressants,” found that “challenges reported by patients quitting antidepressants included feeling overwhelmed by their emotions, finding social situations less enjoyable, and feeling detached and less empathetic towards others.”

The findings were published in Health Expectations.

Related Links:

— “Quick Withdrawal From Antidepressants Can Take Emotional, Cognitive Toll,” Dennis Thompson, HealthDay, January 19, 2024

MedPage Today (1/18, Firth ) reports a study found that “opioid use during pregnancy for pain or opioid use disorder was associated with an increased risk for hospitalizations and emergency department (ED) visits for immune-related conditions in exposed offspring.” Among “more than 400,000 kids born in Western Australia, those with perinatal opioid exposure had an increased risk of perinatal infection…and eczema and dermatitis…compared with non-exposed children,” the research found. The findings were published in JAMA Network Open.

Related Links:

— MedPage Today (requires login and subscription)