Very Positive Initial Findings May Not Hold Up After More Studies.

The Los Angeles Times (10/24, Brown) reports, “In a statistical analysis of nearly 230,000 trials compiled from a variety of disciplines, study results that claimed a ‘very large effect’ rarely held up when other research teams tried to replicate them,” according to research published in the Journal of the American Medical Association.

HealthDay (10/24, Gordon) reports, “When initial findings about an experimental drug or treatment sound too good to be true, they probably are, according to a new study” published in the Journal of the American Medical Association. Investigators “found that after a single study reports large benefits for a new medical intervention, additional studies almost always find a smaller treatment effect.” The researchers “suspect that a small study size contributes to the initially inflated benefits.”

Related Links:

— “Medical studies with striking results often prove false, “Eryn Brown, Los Angeles Times, October 24, 2012.

NIMH: Cost Of Depression In Workplace Estimated At $44B/Year.

Forbes (10/24, Martin) reports, “Depression tops the list of health-related productivity costs in the workplace. That was the finding in a medicalstudy shortly after the economy tanked in the 2008 recession, and it’s no different now.” In fact, “the annual cost of depression is estimated at $44 billion in lost productivity to American companies according to the National Institute of Mental Health.”

Related Links:

— “Tackling Depression at Work as a Productivity Strategy,”Judy Martin, Forbes, October 23, 2012.

Psychiatrists Discuss How Practice Of Psychiatry Is Shifting.

On its website and its “Talk of the Nation” program, NPR (10/23) reports, “The American Psychiatric Association defines a psychiatrist as a medical doctor who conducts psychotherapy and prescribes medications and other medical treatments. With recent developments in the pharmaceutical and insurance industries, the definition of the practice appears to be shifting.” Host Neal Conan discussed the changing role of psychiatry with Richard Friedman, MD, director, Psychopharmacology Clinic, Weill Cornell Medical College, and psychiatrist Steve Balt, editor-in-chief, The Carlat Psychiatry Report. One of the topics discussed was how, with the increased use of antidepressants in recent years, the “use of talk therapy” has declined, a trend driven by “market forces” and managed care.

Related Links:

— “Psychiatrists Shift Focus To Drugs, Not Talk Therapy,NPR, October 22, 2012.

Study Highlights Dads’ Role In Teens’ Sexual Behavior.

The Washington Post (10/23, Rowan) reports that “fathers’ attitudes toward teen sex and the emotional closeness of their relationship with their teens have a sizable influence on their teens’ sexual behavior, separate from the influence of moms, a new review of studies suggests.” According to the article, “the review showed that dads’ attitudes toward teen sexual behavior were linked to the age at which teens first had sex.” Citing the studies in the review, the Post points out that “teens whose dads approved of adolescent sexual activity tended to start having sex earlier than teens whose dads did not approve.” The findings were published last week in the journal Pediatrics.

Related Links:

— “Fathers play key role in teens’ sexual behavior, says study, “Karen Rowan, The Washington Post, October 22, 2012.

Kids With Mental Health Disorders More Likely To Be Bullies.

. HealthDay (10/23, Preidt) reports, “Children with mental health disorders are more likely than other kids to be bullies,” according to a study presented yesterday at the American Academy of Pediatrics meeting. “Researchers analyzed data from children ages 6 to 17 included in the 2007 US National Survey of Children’s Health and found that more than 15 percent were identified as bullies by a parent or guardian, and that children with mental health disorders were three times more likely than their peers to bully other children.”

Related Links:

— “Bullying May Be Linked to Mental Disorders, “Robert Preidt, HealthDay, October 22, 2012.

Victimization Associated With Suicidal Thoughts In Adolescents.

The Los Angeles Times (10/23, Healy) “Booster Shots” blog reports that according to a study published online Oct. 22 in the Archives of Pediatric and Adolescent Medicine, “a youth aged 10 to 17 who reports that he or she has been victimized by peers in the past year is nearly 2 1/2 times likelier to have suicidal thoughts than an adolescent who reports no recent victimization.”

HealthDay (10/23, Mann) reports, “Youth who were sexually assaulted had 3.4 times the risk of thinking about suicide and those who were maltreated had 4.4 times the risk of suicidal ideation during the past year,” the study of “study of nearly 1,200 children and adolescents (aged 10 to 17)” revealed.

MedPage Today (10/23, Petrochko) reports, “Teens who had been polyvictimized — those exposed to seven or more types of harassment — in the past year were nearly six times as likely to think about suicide (OR 5.81, 95% CI 3.09 to 10.15),” the study found. Notably, “youth suicide is the third leading cause of death among adolescents in the US, behind auto accidents and homicide, the authors wrote.”

Related Links:

— “Bullying spurs suicidal thoughts – still more if home support lacks, “Melissa Healy, Los Angeles Times, October 22, 2012.

Small Study: Cyberbullying Rarely The Only Factor Behind Teen Suicides.

HealthDay (10/21, Preidt) reported, “Cyberbullying is rarely the only factor behind teen suicides, according to a small study” presented Oct. 20 at the American Academy of Pediatrics’ national conference. “For the study, the investigators analyzed 41 suicide cases in Australia, Canada, the United Kingdom and the United States.”

MedPage Today (10/21, Neale) reported, “Of 41 cyberbullying-related suicides covered in the news since 2003, the victims were subjected to both online and in-person abuse in 78%,” the study found. “Another 17% involved cyberbullying only and 5% involved traditional in-person bullying only,” researchers reported.

Medscape (10/21, Helwick) reported, “Cyberbullying is defined as bullying using electronic means — primarily the Web and text messaging. It is an extension of traditional bullying, but with the additional element of electronic media, which creates some distance between the bully and his or her target,” the study’s lead author explained. “A marked increase was noted in cyberbullying-related suicides in recent years. Only two or fewer cases occurred per year between 2003 and 2007; this jumped to six in 2008, peaked at 13 in 2011, and was reported at five for the first three months of 2012,” according to the study’s lead author.

Related Links:

— “Cyberbullying Rarely Single Factor in Teen Suicides: Study, “Robert Preidt, HealthDay, October 22, 2012.

Murray Asks For Timeline On Military PTSD Review.

The Hill (10/19, Cox) “Floor Action” blog reported that Sen. Patty Murray of Washington, chairwoman of the Senate Veterans’ Affairs Committee, wants Defense Secretary Panetta “to move to the next step on a timeline for a military-wide review of PTSD and behavioral health diagnoses made since the Iraq and Afghanistan wars.” Panetta “promised to follow up” after some service members were told they didn’t have PTSD by a doctor “trying to keep expenses down” at Joint Base Lewis-McChord, but Murray “said…that the investigation seems to have stalled since being announced on June 13.”

Related Links:

— “Murray seeks answers from Defense on review of PTSD diagnoses, “Ramsey Cox, The Hill, October 19, 2012.

Small Study: “Targeted Rejection” In Teen Years May Lead To Later Chronic Disease.

The Time (10/19, Szalavitz) “Healthland” blog reports, “A new study of teenage girls” published online in the journal of Clinical Psychological Science “shows that ‘targeted rejection,’ in which students are singled out for taunting or personally rejected by a friend, can have measurable effects on the immune system.” In their study of 147 young women aged 15 to 19, investigators “found that girls who had recently been targeted for rejection — which can include everything from bullying and ostracizing to being ‘dropped’ by a peer group or friend — had higher levels of substances indicating activation of genes that produce two specific inflammatory proteins, nuclear factor kappa-beta and inhibitor of kappa-beta.” According to the blog, “If sustained, these changes can increase risk for diabetes, heart disease, stroke, mental illness and some cancers later in life, even among those considered to be at the top of the teen social hierarchy.”

Related Links:

— “How Teen Rejection Can Lead to Chronic Disease Later in Life,”Maia Szalavitz, TIME, October 18, 2012.

Study: US Obesity Rate Up By 70% Since 2000, But Pace Of Increase Slowing.

Reuters (10/19, Norton) reports that according to a study published online Sept. 18 in the International Journal of Obesity, the number of people in the US who are severely obese has risen by 70% over the past decade. However, the study also notes that the rise in the obesity rate has slowed down in recent years. From 2000 to 2010, the percentage of people in the US who were severely obese grew from 4% to nearly 7%. The article notes that more than one-third of American adults are considered obese.

Study: Motivational Counseling Helps Slow Pregnancy Weight Gain In Obese Women. Reuters (10/19, Grens) reports that according to a study published online Oct. 2 in the International Journal of Obesity, motivational counseling can help to curb weight gain in obese pregnant women. By the end of their pregnancies, obese women who received counseling gained approximately 23 pounds, while obese women receiving standard care during their pregnancy gained almost 30 pounds. The study examined 205 obese pregnant women who were randomly assigned to get either motivational counseling on exercise, nutrition, and weight gain, or standard prenatal care.

Related Links:

— “Severe obesity still rising fast in the U.S, “Amy Norton, Reuters, October 18, 2012.