Stress, depression common for women at time of MI and two months later

According to HealthDay (10/16), “For women with myocardial infarction (MI), stress and depression are common at the time of MI and two months later,” a study published in the Journal of the American College of Cardiology shows. Investigators “found that women with MINOCA (myocardial infarction with nonobstructive coronary arteries) were younger and more diverse than women with MI-CAD (myocardial infarction-coronary artery disease).”

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— “Stress, Depression Common Among Women With Myocardial Infarction,”Elana Gotkine, HealthDay , October 16, 2023

Patients Needing Medications For OUD Should Continue To Receive Them Prior To Surgery, Researchers Conclude

Medscape (10/16, Banks, Subscription Publication) reports, “Patients who need medications for opioid use disorder (OUD) should continue to receive them prior to surgery, rather than stopping those drugs, as has been the convention,” according to findings from “a new analysis of more than five million surgeries presented at Anesthesiology 2023.”

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With People Not Taking Antidepressants, People Taking Antidepressants Appear To Lose Similar Amount Of Weight On Semaglutide 2.4 Mg, Analysis Of Four Trials Indicates

MedPage Today (10/16, Haelle) reports, “People taking antidepressants lost a similar amount of weight on semaglutide 2.4 mg (Wegovy) compared with those not taking antidepressants, according to a post-hoc analysis of four STEP trials” presented at the ObesityWeek annual meeting. The study revealed that “participants on antidepressants taking the GLP-1 receptor agonist lost an average 10.7% to 19% of their baseline body weight compared to a 9.5% to 15.9% loss in participants not taking antidepressants.”

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Use Of Mirtazapine, Nortriptyline, And Trazodone Among Hospitalized Patients Appears Tied To Greater Risk Of CDI, Study Suggests

HCPlive (10/16, Brooks) reports, “Hospitalized patients using mirtazapine, nortriptyline, and trazodone are at a greater risk of Clostridioides difficile infection (CDI),” researchers concluded in a study that compared “48,720 patients developed CDI…to 55,615,700 who did not.” The findings were published in the July-Sept. Issue of the journal Arquivos de Gastroenterologia.

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— “Antidepressant Use Linked to Increased Risk of Hospital-Onset C Diff,”Abigail Brooks, HCPlive, October 16, 2023

Substantial Proportion Of Young Children From Low-Income Families Appear To Have Elevated Levels Of Emotional, Behavioral Health Problems Seen In Pediatric Primary Care, Researchers Conclude

MedPage Today (10/16, Henderson) reports, “A substantial proportion of young kids from low-income families had elevated levels of emotional and behavioral health problems seen in pediatric primary care, researchers” concluded in findings published online in JAMA Pediatrics. In the “retrospective cohort study of 15,218 children ages two to six years, fully one-third of children had screening tool scores reflecting clinically elevated levels of emotional and behavioral problems over time.” Additionally, “relative to those whose scores remained low over time, kids in the elevated score groups were more likely to be male, white, have public insurance, have had a social need, and a caregiver with depression,” the study revealed.

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US Regulators Lift Curbs On Reimbursement For Amyloid PET Scans To Diagnose Alzheimer’s Disease

Reuters (10/13, Steenhuysen) reported, “U.S. health officials on Friday lifted curbs on reimbursement of a non-invasive imaging test called amyloid PET used to diagnose Alzheimer’s, ending a once-per-lifetime limitation that clears the way for its use to determine eligibility for new treatments.” These new medications “include Eisai and Biogen’s Leqembi [lecanemab], and an experimental drug from Eli Lilly known as donanemab, which work by removing a protein called beta amyloid from the brain.” The protein clumps “are considered an early hallmark of Alzheimer’s disease that gradually destroy memory and thinking skills. Previously, amyloid positron emission tomography, or PET, scans were only accessible for use in a clinical trial or patient registry.”

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— “US removes coverage curb on PET scans for Alzheimer’s patients,”Julie Steenhuysen, Reuters, October 13, 2023

Internalizing Symptoms Among Latinx Youth During Early Adolescence Relate To Health Behaviors, Outcomes Underlying Cardiometabolic Risk During Middle And Late Adolescence, Survey Study Suggests

HealthDay (10/13, Solomon) reported, “Internalizing symptoms among Latinx youth during early adolescence relate to health behaviors and outcomes underlying cardiometabolic risk during middle and late adolescence,” investigators concluded in the findings of a 547-Hispanic adolescent survey study published online in the Journal of Adolescent: “ Kathleen M. Roche, Ph.D., from the Milken Institute School of Public Health at George Washington University in Washington, D.C., and colleagues examined how Latinx youth’s internalizing symptoms during early adolescence are related to sleep problems, overweight/obesity, sedentary behavior, physical activity, healthy diet, and hypertension or diabetes risk during middle and late adolescence.”

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— “Internalizing Symptoms in Early Teens Tied to Later Cardiometabolic Risk Factors,”Lori Solomon, HealthDay, October 13, 2023

Prevalence Of Neuropsychiatric Symptoms In Patients With Systemic Autoimmune Rheumatic Diseases Appears Higher Than Previously Recognized, Researchers Say

Healio (10/12, Martin) reports, “The prevalence of neuropsychiatric symptoms in patients with systemic autoimmune rheumatic diseases is significantly ‘higher and more wide-ranging’ than previously recognized, according to” findings published online in the journal Rheumatology. After analyzing data from the INSPIRE project, investigators concluded that “barriers to reporting neuropsychiatric symptoms in patients with systemic autoimmune rheumatic diseases include limited knowledge and subjectivity.” What’s more, “most patients reported not being asked about their mental health by physicians.”

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— “Psychiatric symptom burden in SARDs higher, ‘more wide-ranging’ than previously recorded,”Erich Martin, Healio , October 12, 2023

Researchers release novel catalog of more than 3,000 types of brain cells

The Washington Post (10/12, Johnson) reports researchers on Thursday released “the most detailed and complex portrait yet of the human brain in a dazzling catalog of more than 3,000 types of brain cells that collectively give rise to emotion, thought, memory and disease.” The findings, developed under the Brain Research Through Advancing Innovative Neurotechnologies initiative and published in 21 studies in Science and other journals, “are starting to open up the black box of the brain by providing an initial parts list for the most complex organ scientists have ever studied.”

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Adults With Atopic Dermatitis May Have Significantly Higher Prevalence Of Anxiety, Depression, And OCD Across All Severities Of The Skin Disorder, Researchers Conclude

MedPage Today (10/12, Bankhead) reports, “Adults with atopic dermatitis (AD) had a significantly higher prevalence of anxiety, depression, and obsessive-compulsive disorder (OCD) across all severities of the skin disorder,” investigators concluded in findings from “a large retrospective analysis” published online in the Journal of the European Academy of Dermatology and Venereology. The study “identified 625,083 adults with AD, who were matched to 2,678,888 adults without AD.”

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