Healio (1/12, Rhoades) reports, “Certain depressive symptoms experienced during midlife were tied to a greater risk for dementia, with some increasing the risk by around 50%, according to recently published data.” One study author said the results “show that dementia risk is linked to a handful of depressive symptoms rather than depression as a whole. … This symptom-level approach gives us a much clearer picture of who may be more vulnerable decades before dementia develops.” “Six depressive symptoms emerged as robust midlife indicators of increased dementia risk: Losing confidence in myself” , “Not able to face up to problems” , “Not feeling warmth and affection for others”, “Nervous and strung-up all the time”, “Not satisfied with the way tasks are carried out”, and “Difficulties concentrating” . Associations were independent of established dementia risk factors, including APOEε4 status, cardiometabolic conditions,”
Related Links:
— “Six depressive symptoms during midlife raise dementia risk,”Andrew (Drew) Rhoades , Healio , January 12, 2026