Medscape (8/14, Yasgur) reports that research suggests “clozapine…reduces mortality and protects against self-harm in patients with treatment-resistant schizophrenia.” Researchers “found a nearly twofold higher mortality rate among patients with treatment-resistant schizophrenia who were not being treated with clozapine, compared with those treated with the” medication. The findings also “suggest a deleterious effect of other antipsychotics on self-harm compared to clozapine.” The research was published online July 28 in the American Journal of Psychiatry.
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