Medscape (1/28, Franki, Subscription Publication) reports, “The Food and Drug Administration is strengthening a previous warning regarding the uncommon risk of serious bowel complications associated with the schizophrenia medication clozapine.” According to an FDA press release, “clozapine affects bowel function in a majority of patients, and constipation is a common adverse event associated with clozapine use.” These effects “can uncommonly progress to serious bowel complications, including complete bowel blockage, and can result in hospitalization or even death if the constipation is not diagnosed and treated quickly.”
Related Links:
— “FDA Strengthens Bowel Complication Warning for Clozapine, “Lucas Franki, Medscape, January 28, 2020