MedPage Today (11/19, George ) reports, “Genetic risk for Alzheimer’s disease and dementia appeared to be partly offset by high levels of cardiorespiratory fitness, U.K. Biobank data suggested.” Investigators found that “overall, high cardiorespiratory fitness was associated with better global and domain-specific cognitive functions and lower risk of dementia in both middle-age and older adults.”
The data indicated that “the incidence rate ratio of all-cause dementia was 0.60…for high versus low cardiorespiratory fitness. Dementia onset was delayed by 1.48 years…in the high fitness group.”
Meanwhile, “among people with moderate or high genetic dementia risk scores, high cardiorespiratory fitness attenuated dementia risk by 35%…compared with low fitness.” The findings were published in the British Journal of Sports Medicine.
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