Neurology Advisor (4/7, Lopez) reports, “Greater physical activity levels and less sedentary behavior protect against the risk of developing neuropsychiatric diseases, according to study results presented at the 2025 American Academy of Neurology (AAN) annual meeting.” Researchers found that “moderate to vigorous physical activity energy expenditure had a protective effect against neuropsychiatric diseases, while increased sedentary behavior was a risk factor.” Specifically, they noted that “proteomic and metabolic analyses confirmed the significant effect of physical activity on the peripheral biomarkers, high-density lipoproteins (HDL) and integrin alpha V (ITGAV) proteins. Inflammation and metabolic processes were shown to mediate the relationship between physical activity and risk of neuropsychiatric diseases.”
Related Links:
— “Greater Physical Activity May Lower Risk for Neuropsychiatric Diseases,”Maria Arini Lopez, Neurology Advisor, April 7, 2025