Increasing exercise in middle age may protect against Alzheimer’s disease

HealthDay (5/2, Thompson ) reported a study found that “people who increased their physical activity to meet recommended guidelines between ages 45 and 65 had less accumulation of amyloid beta, a toxic protein that forms plaques in the brains of” patients with Alzheimer’s. Researchers observed the link was dose-dependent, meaning that the “more people increased their activity, the greater the reduction in amyloid beta in their brains. Active people also showed less age-related shrinkage in brain regions associated with memory and Alzheimer’s.” Researchers concluded, “These findings reinforce the importance of promoting physical activity in middle age as a public health strategy for Alzheimer’s prevention.” The study was published in Alzheimer’s & Dementia.

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— “Middle-Age Exercise Protects Brain Against Alzheimer’s,” Dennis Thompson, HealthDay, May 2, 2025

Posted in In The News.