Psychiatric News (2/27) reported a study found that “transgender youth who initiated testosterone therapy didn’t experience increased anger or irritability a year later – in fact, some demonstrated reduced aggression.” The study included “178 gender-diverse adolescents and young adults…in the United States who initiated testosterone therapy. All the youth had completed puberty and had no exposure to puberty blockers.” Researchers observed that “on average, self-reported levels of anger, aggression, irritability, externalizing problems, and oppositional defiant problems were within normal ranges at baseline…and they remained about the same 12 months after initiating testosterone therapy.” However, “45.5% of youth reported slightly elevated anger and/or externalizing behaviors at baseline, and their average levels of these behaviors dropped to the normal range at 12 months.” The study was published in the Journal of Adolescent Health.
Related Links:
— “Testosterone Doesn’t Increase Irritability in Transgender Youth, Psychiatric News , February 27, 2026