STAT (6/9, Lloreda) reports research indicates that “a low dose of” nitrous oxide may help improve symptoms in patients with treatment-resistant depression [TRMD], investigators concluded in a study that “recruited 24 patients with TRMD, who were randomized in a crossover study to receive placebo, the low dose, or the high dose of laughing gas for one hour.” Eventually, “researchers then evaluated depressive symptoms of the 20 participants who completed all three sessions with a variety of questionnaires up to two weeks after each treatment.” The study team “found that a low dose of nitrous oxide…was just as effective at improving depression as a higher dose in patients with treatment-resistant depression, with” fewer “adverse side effects after two weeks.” The findings were published online June 9 in Science Translational Medicine.
Related Links:
— “A safer, low dose of laughing gas may be enough to help some patients with major depression, study finds “Claudia López Lloreda, STAT, June 9, 2021