Medscape (9/12, Cassels) reports that, according to a study published in the September issue of the Journal of Occupational and Environmental Medicine, “negative working conditions, including low job satisfaction, little control, and a lack of appreciation by employers, are responsible for a sizeable proportion of depression in middle-aged adults.” Researchers arrived at this conclusion after analyzing “the relationship between a large number of working conditions and depressive symptoms on the basis of four waves of data collection during a period of 15 years in 1889 US workers aged 25 years and older.”