New synthetic opioid may require multiple naloxone doses to treat overdose

CNN (8/29, Howard) reports, “A group of novel synthetic opioids emerging in illicit drugs in the United States may be more powerful than fentanyl, 1,000 times more potent than morphine, and may even require more doses of the medication naloxone to reverse an overdose, a new study suggests.” The new opioid, nitazenes, “are a synthetic opioid, like fentanyl, although the two drugs are not structurally related. In the small study published Tuesday in the journal JAMA Network Open most of the patients who overdosed on nitazenes received two or more doses of the opioid overdose reversal drug naloxone, whereas most patients who overdosed on fentanyl received only a single dose of naloxone.”

Related Links:

— “Emerging group of synthetic opioids may be more potent than fentanyl, study warns,”Jacqueline Howard, CNN, August 29, 2023

Posted in In The News.