HCP Live (1/22, Derman) reports, “In a new study, older adults with treatment-resistant schizophrenia reported significantly fewer adverse events of clozapine than young adults.” Investigators “obtained data from a retrospective cohort study in a large psychiatric institute in the Netherlands, including 284 participants diagnosed with treatment-resistant schizophrenia who started taking clozapine between 2011 and 2020,” and “compared the number and type of adverse events, as well as the number of treatment discontinuations and the time until discontinuation due to adverse events, of older adults versus younger adults.” The findings were published in the International Journal of Geriatric Psychiatry.
Related Links:
— “Young Adults at Greater Risk of Adverse Events with Clozapine than Older Adults,” Chelsie Derman, HCP Live, January 22, 2024