MedWire (4/11, Robertson) reports, “Depression is associated with a significantly increased risk for dementia among patients with type 2 diabetes,” according to a study published online in the Archives of General Psychiatry. After analyzing data on some 20,000 patients with diabetes who partook in the Diabetes and Aging Study, researchers found that “depression at baseline was associated with a 2.02-fold greater risk for dementia compared with those without diabetes, after adjustment for covariates.”

Related Links:

— “Depression impacts on dementia risk in diabetes,”Sally Robertson, MedWire News, April 10, 2012.

The Los Angeles Times (4/11, Kaplan) “Booster Shots” blog reports, “Nearly two-thirds of Americans who are obese try to lose weight, and about 40% of them actually succeed. How did they do it? The old-school way: By eating less, exercising more and switching to more healthful foods,” according to a study published in the American Journal of Preventive Medicine. Researchers examined 4,021 adults who had been obese between 2001 and 2006 before participating in the study. As the blog post notes, “2,523 — or 63% — said they had tried to lose weight in the previous 12 months. And among them, 1,026 — or 41% — were able to shed at least 5% of their body weight…Even better, 510 people — or 20% — succeeded in losing at least 10% of their body weight.” Among participants who lost at least 10%, exercise and healthier eating — not shortcuts –were typical practices.

The Time (4/11, Sifferlin) “Healthland” blog notes that “the most popular strategies were eating less, exercising more, eating less fat and switching to lower-calorie foods. People who used commercial weight-loss programs and prescription weight-loss pills also saw success, but only a small portion of the study participants used them.” Also covering the story are MedPage Today (4/11, Fiore), WebMD (4/11, Mann) and HealthDay (4/11, Doheny).

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MedWire (4/10, Cowen) reports that according to a study published April 1 in the American Journal of Psychiatry, “methamphetamine users are at increased risk for developing schizophrenia.” After examining “data from California inpatient hospital discharge records for the period 1990-2000 to identify 42,412 patients with methamphetamine, 39,390 with cocaine, 408,604 with alcohol, 56,844 with opioid, 23,335 with cannabis use disorders, and a comparison group of 188,732 patients with appendicitis,” investigators “found that, compared with appendicitis patients, methamphetamine users had the greatest risk for schizophrenia (hazard ratio [HR]=9.37), followed by cannabis users (HR=8.16), cocaine users (HR= 5.84), those with alcohol use disorder (HR=5.56), and opioid users (HR=3.60), after accounting for age, gender, ethnicity, and other variables.”

Related Links:

— “Methamphetamine use may increase schizophrenia risk,”Mark Cowen, MedWire News, April 10, 2012.

The Los Angeles Times (4/8, Murphy) reported that “in a small but growing number of cases across the nation, lawyers are blaming the US military’s heavy use of psychotropic drugs for their clients’ aberrant behavior and related health problems.” According to the Times, “more than 110,000 active-duty Army troops last year were taking prescribed antidepressants, narcotics, sedatives, antipsychotics and anti-anxiety drugs. … Nearly 8% of the active-duty Army is now on sedatives and more than 6% is on antidepressants — an eightfold increase since 2005.”

VA Part Of Effort To Reduce Painkiller Usage. On its front page, the New York Times (4/9, A1, Meier, Subscription Publication) reports, “Data suggests that hundreds of thousands of patients nationwide may be on potentially dangerous dosages” of powerful painkillers like oxycodone. The “Departments of Defense and Veterans Affairs are trying new programs to reduce use among active-duty troops and veterans. Various states are experimenting with restrictions.”

Related Links:

— “A fog of drugs and war,”Kim Murphy, Los Angeles Times, April 7, 2012.

In a special analysis piece, the New York Times (4/9, SR3, Harmon, Subscription Publication) reports, “The report by the Centers for Disease Control and Prevention that one in 88 American children have an autism spectrum disorder has stoked a debate about why the condition’s prevalence continues to rise,” conceding that the increase could possibly be attributed to better methods of detection or perhaps to some unknown factor in the environment. However, last month’s report also “appears to be serving as a lightning rod for those who question the legitimacy of a diagnosis whose estimated prevalence has nearly doubled since 2007.” Meanwhile, an American Psychiatric Association workgroup “in charge of autism criteria for the new version of the Diagnostic and Statistical Manual of Mental Disorders has proposed changes that would exclude some who currently qualify, reducing the combination of behavioral traits through which the diagnosis can be reached from a mind-boggling 2,027 to 11, according to one estimate.”

Related Links:

— “The Autism Wars,”Amy Harmon, The New York Times, April 7, 2012.