HealthDay (2/28, Thompson ) said that people who “regularly exercise have better mental and brain health, researchers will report in early April at the annual meeting of the American Academy of Neurology in San Diego and online.” Investigators found that “moderate to vigorous physical activity reduces risk of dementia, stroke, anxiety, depression and sleep disorders.” Researchers said, “With our large number of participants and the use of devices that provide objective measurements of activity levels, these results will have implications for assessing risk factors and developing interventions to prevent the development of these diseases.”

Related Links:

— “Physical Activity Linked to Better Mental, Brain Health,” Dennis Thompson, HealthDay, February 28, 2025

Psychiatric News (2/28) reported a study suggests that “patients with dementia taking some antidepressants,particularly selective serotonin reuptake inhibitors (SSRIs), experienced faster cognitive decline compared with those not taking these medications.” According to the study, “adults taking antidepressants experienced faster cognitive decline during follow-up compared with non-use (an additional 0.3-point loss on the MMSE per year). Among adults who had severe dementia at baseline, those taking antidepressants experience an additional 1.5-point loss on the MMSE per year.” In particular, “three SSRIs on the list – escitalopram, sertraline, and citalopram – were associated with greater cognitive decline compared with non-use. Compared with sertraline, escitalopram presented with faster cognitive decline, while citalopram was linked to a slower cognitive decline.” The study was published in BMC Medicine.

Related Links:

— “SSRIs Associated With Faster Cognitive Decline in Patients With Dementia,” Psychiatric News, February 28, 2025

CNN (3/10, Valinsky ) reports that CVS is set to open about a dozen smaller stores this year, each “about…half the size of its traditional layout and” that “have only a pharmacy.” The initiative is part of CVS’ broader turnaround strategy, which includes over 1,000 store closures and layoffs as the company adapts to changes in the retail pharmacy industry. A CVS spokesperson stated that the smaller stores will cater to community pharmacy needs while providing some over-the-counter products.

Forbes (3/9, Japsen ) reports the news “comes as CVS’ main rival Walgreens Boots Alliance works on a financial turnaround, closes hundreds of stores and prepares for private ownership after Walgreens last week announced a $10 billion sale to Sycamore Partners.” The push for “new sizes and formats has taken on more urgency because both companies have large amounts of debt and face escalating pressure from flat or falling sales of general merchandise in the front of their stores.”

Related Links:

— “CVS is opening smaller stores that only have pharmacies,” Jordan Valinsky, CNN, March 10, 2025

MedPage Today (2/3, George ) reports “headache diagnoses were persistently associated with an increase in attempted and completed suicides, a population study of more than 100,000” patients with headache “in Denmark showed.” Researchers found that “across four types of headache – migraine, tension-type headache, post-traumatic headache, and trigeminal autonomic cephalalgia – the association was robust.” The findings were published in JAMA Neurology.

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— MedPage Today (requires login and subscription)

Psychiatric News (2/3) reports “kindergarten-ag e children who have fathers with depression are more likely than children not exposed to paternal depression to have behavioral problems and poor social skills several years later, a study” found. The researchers said their findings “suggest the need for interventions supporting school-aged children exposed to paternal depression. … Pediatricians, with their frequent contact with families, are well-positioned to address these important needs.” The findings were published in the American Journal of Preventive Medicine.

Related Links:

— “Fathers’ Depression May Affect Children’s Behavior, Psychiatric News, January 3, 2025