The Boston Globe (10/19, Finucane) reported a study published in JAMA Network Open found that people with the ApoE4 gene and who also have chronic inflammation have a higher risk of contracting Alzheimer’s disease. The researchers “used data from the Framingham Heart Study, which includes more than 3,000 human subjects.”

Related Links:

— “BU researchers examine role of inflammation in Alzheimer’s disease, “Martin Finucane, The Boston Globe, October 19, 2018.

Neurology Advisor (10/18) reports researchers found in a medical literature review that “for most patients, treatment with clozapine can produce a slight reduction in the antipsychotic-induced movement disorder tardive dyskinesia and can greatly reduce the disorder’s severity in patients with moderate to severe cases.” The findings were published online Sept. 18 in the Journal of Clinical Psychiatry.

Related Links:

— “Clozapine Monotherapy Improves Antipsychotic-Induced Tardive Dyskinesia, Neurology Advisor, October 18, 2018.

Anne Zink, MD, “the immediate past president of the Alaska chapter of the American College of Emergency Physicians,” writes in STAT (10/18) “First Opinion” about “psychiatric boarding,” the practice of emergency departments holding patients with mental health issues “because no appropriate mental health care is available.” Dr. Zink outlines different initiatives that aim to address the problem before concluding that “the better able we are to treat patients with mental and behavioral issues, communicate and collaborate effectively, and match patients with the appropriate resources outside of the emergency department, the better off our health system and our patients will be.”

Related Links:

— “Mental health patients, with nowhere else to go, are overwhelming emergency departments, “Anne Zink, STAT, October 18, 2018.

The New York Times (10/17, Bakalar) reports, “Having pre-eclampsia – dangerously high blood pressure during pregnancy – is linked to an increased risk for dementia later in life,” research indicated.

MedPage Today (10/17) reports the condition is particularly tied to “vascular dementia, later in life,” researchers concluded in an analysis involving “over one million women over a median of 21 years.” The findings were published online in the BMJ. The authors of an accompanying editorialobserved, “What the study endorses is some commonality between preeclampsia and vascular dementia: both are propagated by preexisting cardiovascular risk factors and have a pathogenesis that targets blood vessels – something not seen with the Alzheimer’s variant of dementia, for example.” HealthDay (10/17, Thompson) also covers the study.

Related Links:

— “High Blood Pressure of Pregnancy Tied to Dementia Later in Life, “Nicholas Bakalar, The New York Times, October 17, 2018.

Reuters (10/16, Carroll) reports researchers found that “people with restless legs syndrome may be more likely to think about suicide or to actually make plans to take their own lives, compared to people without the troublesome condition.” The findings were published in Sleep Medicine.

Related Links:

— “Restless legs syndrome linked with risk for suicidal thoughts, “Linda Carroll, Reuters, October 16, 2018.