Prevalence Of Treatment-Resistant Depression Appears To Vary By Sex, Race, And Age, Data Indicate

Healio (12/10, Gramigna) reported, “Treatment-resistant depression [TRD] prevalence varied by sex, race and age,” investigators concluded in a study that “sought to outline TRD prevalence using two large U.S. claims databases, Humana (n = 296,055 patients) and Optum (n = 277,941).” The study team “analyzed data of patients aged 18 years or older who had pharmaceutically treated depression (PTD)…with at least one major depressive disorder diagnosis based on ICD-10-CM criteria and one antidepressant prescription filled in 2018.” The findings of the “cross-sectional study” were published online Nov. 30 in the Journal of Clinical Psychiatry. “ Females, middle-aged adults, and White patients had higher risk of TRD. The median time from index antidepressant use to TRD was about 6 months in incident PTD patients.”

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— “Sex, race, age impact risk for treatment-resistant depression “Joe Gramigna, Healio, December 10, 2021

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