Psychiatric News (3/24) reports a study found that “endometriosis may significantly increase the risk of major depressive disorder (MDD) and vice versa in premenopausal women.” In one analysis, researchers observed that “women with endometriosis had a 39% increased risk of MDD compared with those without endometriosis. In the parallel analysis, women with MDD had a 30% increased risk of endometriosis compared with those without MDD.” According to researchers, “metabolic biomarkers linked with triglyceride levels, insulin resistance, and liver function partially explained the bidirectional association between endometriosis and MDD.” They concluded, “These findings underscore the importance of considering mental health in the management of endometriosis and vice versa.” The study was published in the Journal of Affective Disorders.
Related Links:
— “Endometriosis and Major Depressive Disorder Are Linked to One Another, Psychiatric News , March 24, 2026