Psychiatric News (7/15) reports that “taking metformin may help” adolescents with overweight or obesity “who take antipsychotic medications avoid the weight gain commonly associated with the drugs, according to researchers.” The investigators said, “Based on our assessment…of the risks and benefits of adding [metformin] to a brief healthy lifestyle intervention among youth with [bipolar disorder] who have overweight or obesity, clinicians should strongly consider prescribing [metformin] in conjunction with [second-generation antipsychotics].” The findings (PDF) were published by the Patient-Centered Outcomes Research Institute.
Related Links:
— “Metformin May Curb Weight Gain in Youth Who Take Antipsychotics,Psychiatric News, July 15, 2025