Patients With Cystic Fibrosis Or Primary Ciliary Dyskinesia, As Well As Their Caregivers, Appeared To Be At Increased Risk Of Developing Mental Illnesses During COVID-19 Pandemic, Small Study Suggests

According to HCPlive (4/21, Walter), research indicates that “patients with cystic fibrosis or primary ciliary dyskinesia, as well as their caregivers, were at an increased risk of developing mental illnesses like depression or anxiety during the ongoing COVID-19 pandemic.” Included in the 110-patient study were “110 patients, 10 with cystic fibrosis, 31 with primary ciliary dyskinesia, 52 cystic fibrosis caregivers, and 17 primary ciliary dyskinesia caregivers.” The findings were published online April 21 in the journal Pediatric Pulmonology.

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— “Caregivers, Patients With Cystic Fibrosis, Primary Ciliary Dyskinesia at Elevated Risk of Mental Illness “Kenny Walter, HCPlive, April 21, 2023

Young People With Schizophrenia Appear To Have Elevated Risk For Sudden Cardiac Death, Research Suggests

Healio (4/20, Firment) reported, “Young people with schizophrenia had elevated risk for sudden cardiac death, and biopsychosocial factors related to social isolation impacted the cardiac risk factor burden in individuals with schizophrenia, researchers” concluded in a study also revealing that “among young people with sudden cardiac death who were referred for autopsy, individuals with schizophrenia were more likely to have nonischemic cardiomyopathy compared with individuals without schizophrenia.” The findings of the 579-individual postmortem study were published online in the journal JACC: Clinical Electrophysiology.

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— “Schizophrenic individuals have increased risk for sudden cardiac death “Hunter Firment, Healio, April 20, 2023

Rate Of Suspected Suicides, Suicide Attempts By Poisoning Among Young People Rose Sharply During Pandemic, Research Suggests

CNN (4/20, Christensen) reports, “The rate of suspected suicides and suicide attempts by poisoning among young people rose sharply during the Covid-19 pandemic,” with the rate increasing 73% “from 2019 to 2021” in “children 10 to 12 years old,” according to an analysis published online April 21 in the CDC’s Morbidity and Mortality Weekly Report. The study examined “what the National Poison Data System categorized as ‘suspected suicides’ by self-poisoning for 2021 among people ages 10 to 19; the records included both suicide attempts and deaths by suicide.” The data revealed that “attempted suicides and suicides by poisoning increased 30% in 2021 compared with 2019, before the pandemic began.”

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— “Suicides and suicide attempts by poisoning rose sharply among children and teens during the pandemic “Jen Christensen, CNN , April 20, 2023

Depression Diagnosis Before, After Breast Cancer Diagnosis Appeared Associated With Worse Survival Outcomes, Study Finds

Healio (4/20, Southall) reports, “A depression diagnosis before and after a breast cancer diagnosis appeared associated with worse survival outcomes, according to study results.” The research indicates “that early detection and continued management of depression are imperative to improve patient survival, researchers concluded.” The findings were published in Cancer.

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— “Depression before, after diagnosis linked to higher risk for breast cancer death “Jennifer Southall, Healio , April 20, 2023

Suspected Suicide Attempts Tied To Marijuana Overdoses Have Been Steadily Increasing Over The Past Decade, Study Indicates

HealthDay (4/20, Thompson) reports, “Suspected suicide attempts linked to marijuana overdoses have been steadily increasing over the past decade,” investigators concluded.

HCPlive (4/20, Walter) reports researchers “described suicidal cannabis exposures reported to US poison centers between 2009-2021 and compared case characteristics before and during the pandemic.” They then examined some “18,698 intentional, suspected suicidal cannabis exposures between 2009-2021.” The findings were published online April 19 in a research letter in JAMA Network Open.

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— “Could Better Access to Marijuana Be Linked to Rising Suicide Rates? “Dennis Thompson, HealthDay, April 20, 2023

People Who Directly Experience Sexual Trauma May Have Lower Reward Responsiveness Compared With Those Who Experience Other Types Of Trauma, Research Suggests

Healio (4/19, VanDewater) reports, “People who directly experienced sexual trauma had lower reward responsiveness compared with those who experienced other types of trauma,” researchers concluded in a study that “enrolled 223 undergraduate students with a history of trauma.” The findings were presented in a poster at the Anxiety and Depression Association of America Conference.

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— “Direct sexual trauma associated with impaired reward response “Kalie VanDewater, Healio, April 19, 2023

Interpersonal Psychotherapy May Be Better Option For Reducing Depressive Symptoms Than Enhanced Usual Care For Pregnant Individuals, Researchers Say

According to HCPlive (4/19, Walter), “research suggests interpersonal psychotherapy is a better option for reducing depressive symptoms than enhanced usual care for pregnant individuals.” Investigators “evaluated depression improvement among” 234 “pregnant individuals from diverse backgrounds randomized to brief interpersonal psychotherapy compared to enhanced usual care.” The findings were published online April 19 in JAMA Psychiatry.

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— “Interpersonal Psychotherapy Reduces Depression Symptoms of Pregnant Women “Kenny Walter, HCPlive, April 19, 2023

Rate Of “Profound” Autism Cases Rising, Albeit Far More Slowly Than Milder Autism Cases, Report Concludes

The AP (4/19, Sherman) reports, “As autism diagnoses become increasingly common, health officials have wondered how many” children in the US “have relatively mild symptoms and how many have more serious symptoms, such as very low IQ and inability to speak.” Now, “a first-of-its-kind study…shows the rate of such ‘profound’ autism is rising, though far slower than milder autism cases.” The study revealed that “the rate of profound diagnoses grew from about three cases per 1,000 children in 2000 to about five cases per 1,000 in 2016,” whereas “the rate of kids diagnosed with milder forms of autism grew from 4 per 1,000 to 14 per 1,000 over those years.”

According to HealthDay (4/19, Murez), “For the new report, the CDC analyzed 2000-2016 data from the Autism and Developmental Disabilities Monitoring Network for more than 20,000 children aged eight with autism,” also finding that “children with profound autism were more likely to be female, from racial and ethnic minority groups, of low socioeconomic status, born preterm or with low birth weight, and have self-injurious behaviors and seizure disorders.” The findings were published online April 19 in the journal Public Health Reports.

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— “Study: Milder autism far outpacing ‘profound’ diagnoses “Mike Stobbe, AP , April 19, 2023

More Students From Middle School To High School Misusing Medications Prescribed For AD/HD, Research Suggests

NBC News (4/18, Lovelace) reports, “More students from middle school to high school are misusing” medications prescribed for attention-deficit/hyperactivity disorder (AD/HD), “amid an increasing number of children being diagnosed with the condition in the” US, research indicates. In fact, “at some schools, as many as one in four students reported misusing” AD/HD medications “in the previous year – meaning they used the medications without a” physician’s “prescription or for nonmedical reasons, according to the” findings published online April 18 in JAMA Network Open.

CNN (4/18, LaMotte) reports, “The study analyzed data collected between 2005 and 2020 by Monitoring the Future, a federal survey that has measured drug and alcohol use among secondary school students nationwide each year since 1975.” In this study’s data set, “questionnaires were given to more than 230,000 teens in eighth, 10th and 12th grades in a nationally representative sample of 3,284 secondary schools.” Study lead author Sean Esteban McCabe, director of the Center for the Study of Drugs, Alcohol, Smoking and Health at the University of Michigan in Ann Arbor, stated, “This study is a major wake-up call.”

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— “Up to 1 in 4 students misuse ADHD drugs, study finds “Berkeley Lovelace Jr., NBC News, April 18, 2023

Keeping HbA1c measures under 9% may lower risk for dementia

MedPage Today (4/17, Monaco) reports, “Based on over a quarter of a million patients, those who kept more than half of their hemoglobin A1c (HbA1c) measures under 9% saw a significantly lower risk for dementia compared with those who had the majority of measurements over this threshold,” investigators concluded in findings published online in JAMA Neurology. The study revealed that “patients who had more than half of HbA1c measures between 9% to just under 10% saw a 31% increased risk for dementia than those with less than half of their measures in this range.” Meanwhile, patients “who had more than half of their HbA1c readings over 10% had a 74% higher risk for dementia than those with less than half of their measures in this category.”

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