Dementia In Patients With Severe, Extremely Treatment-Resistant Schizophrenia Is A Distinct Cognitive Syndrome, Research Indicates

Psychiatry Advisor (5/13, Kuhns) reports that research indicates that “dementia in” patients with “severe, extremely treatment-resistant schizophrenia is a distinct cognitive syndrome that is not adequately explained by Alzheimer disease (AD), other neurodegenerative dementias, antipsychotic exposure, cardiometabolic risk factors, poor effort, premorbid intellectual disability, or long-term institutionalization.” Investigators came to this conclusion after using data from New York state hospitals to study “continuously hospitalized adults with schizophrenia,” all of whom had been “hospitalized for at least 5 years.” The findings were published in JAMA Psychiatry.

Related Links:

— “Dementia in Schizophrenia Reflects Intrinsic Disease Not Neurodegeneration,”Lisa Kuhns, Psychiatry Advisor, May 13, 2026

Posted in In The News.