Patients With Sjögren’s Disease Demonstrate Increased Risk For Attempted Suicide, Study Finds

Healio (6/4, Cooper ) reports a study found that “patients with Sjögren’s disease demonstrate a ‘pronounced risk’ for attempting suicide, with a hazard ratio of 18.054 compared with a general population cohort.” Researchers observed the “incidence rate of suicide attempts was statistically significantly higher among patients with Sjögren’s disease: 0.247 per 100 person-years vs. 0.014 in the comparison group. In a fully adjusted Cox regression, patients with Sjögren’s disease had a hazard ratio of 18.054for suicide attempts vs. the comparison group.” Researchers noted, “It is not uncommon for individuals with [Sjögren’s syndrome] to experience a decline in [health-related quality of life] to levels likened to, or even worse than, death.” They added, “These revelations bear significant weight for health care practitioners tending to patients with Sjögren’s syndrome, arming them with empirical evidence to counsel patients on the heightened suicide attempt risks.” The study was published in Scientific Reports.

Related Links:

— “Patients with Sjögren’s disease demonstrate significant risk for suicide attempt,”Justin Cooper, Healio, June 4, 2025

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