Depression severity at baseline, end of treatment predict relapse among youth

Healio (3/6, Demko) reports, “Among children and teenagers with major depressive disorder [MDD], those with comorbid dysthymia and higher levels of residual symptoms after acute treatment are at greater risk for relapse,” researchers concluded in a study involving “102 youth aged 7 to 18 years with major depression who responded to 12 weeks of fluoxetine and then were randomly assigned to continue or switch to placebo for six more months.” The findingswere published online Feb. 20 in the Journal of Clinical Psychiatry.

Related Links:

— “Depression severity at baseline, end of treatment predict relapse among youth,” Kennard BD, et al., Healio, March , 2018.

Pressured To Diet During Adolescence May Have A Higher Risk Of Obesity, Eating Disorders

Reuters (3/6, Rapaport) reports, “Adults who were pressured by their parents to diet during adolescence may have a higher risk of obesity and eating disorders as adults than people who weren’t urged to lose weight as teens,” researchers found after examining “data from eating surveys that 556 participants completed in school when they were 15 years old on average, as well as results from online surveys they completed as adults 15 years later.” The findings were published online in Pediatrics. The study provides “fresh evidence that even well-intended efforts by parents to encourage kids to slim down can backfire, said” the “co-author of an accompanying editorial.” HealthDay (3/6, Gordon) also covers the study.

Related Links:

— “Dieting pressure in teen years tied to food and weight problems later,” Lisa Rapaport, Reuters, March 6, 2018.

Opioid Crisis Overshadows A Cocaine Resurgence

The New York Times (3/5, Frakt, Subscription Publication) reports that opioid abuse is not the only “significant drug problem” in the US, because “among illicit drugs, cocaine is the No. 2 killer and claims the lives of more African-Americans than heroin does.” The story cites a recent study published in The Archives of Internal Medicine where “researchers from the National Cancer Institute and the National Institute on Drug Abuse found that drug-related deaths have grown across all racial groups and among both men and women.”

The analysis indicates” that between 1999 and 2015, overdose deaths of any kind of drug for Americans 20 to 64 years old increased 5.5 percent per year.” Among “non-Hispanic black Americans, cocaine has been a larger problem than heroin for nearly 20 years.”

Related Links:

— “Overshadowed by the Opioid Crisis: A Comeback by Cocaine,” Austin Frakt, New York Times, March 5, 2018.

Number Of Minors Hospitalized For Opioid Poisonings Or Overdoses May Be Increasing

The AP (3/5, Tanner) reports researchers found that a growing number of minors in the US are being hospitalized because of opioid poisonings or overdoses, according to a study published in Pediatrics. The study found that such “hospitalizations were most common among kids aged 12-17 and those aged 1 to 5.”

CNBC (3/5, Lovelace) reports that the researchers found that “the number of pediatric opioid hospitalizations requiring intensive care nearly doubled to 1,504 patients between 2012 and 2015, from 797 patients between 2004 and 2007.”

HealthDay (3/5, Norton) reports that Dr. Sheryl Ryan, the chief of adolescent medicine at Penn State Health Milton S. Hershey Medical Center, wrote in an accompanying commentary, “This epidemic is not limited to adults.” Ryan advised parents to store prescription opioids appropriately and to dispose of unused opioids, so they could not be accidentally ingested or abused by their children.

Additional coverage is provided by: NBC News (3/5, Fox), CNN (3/5, Lieber), TIME (3/5, MacMillan), Newsweek (3/5, Lee), and Medscape (3/5, Hackethal).

Related Links:

— “Opioid poisonings, overdoses send more US kids to hospitals,” LINDSEY TANNER, Associated Press, March 5, 2018.

Depression In Teens May Manifest Itself As Physical Ailments, Anger, Or Irritability

The Wall Street Journal (3/5, Bernstein, Subscription Publication) reports that in an effort to help parents discern whether their adolescent children are depressed or merely moody, the American Academy of Pediatrics updated its guidelines in February to recommend that youngsters age 12 and older be screened by their pediatricians for depression. The Journal also points out that depression can manifest itself in teens as physical ailments such as headaches or in anger or irritability. Teens who are having difficulty in several areas of their life and who don’t seem to be getting any enjoyment out of anything may be suffering from depression.

Related Links:

— “How to Spot Teenage Depression,” Elizabeth Bernstein, Wall Street Journal, March 5, 2018.

Gun Availability A Better Explanation For Mass Shootings Than Mental Illness

In a perspective piece in the Washington Post (3/1, Morris) “Health & Science” blog, Nathaniel Morris, MD, a resident physician in psychiatry at the Stanford University School of Medicine, wrote that “evidence suggests that gun availability is a far better explanation for mass shootings than mental illness and that gun regulations targeted exclusively toward people with mental health issues will have minimal impact on the American epidemic of gun homicides.” Dr. Morris concluded that “when it comes to the link between guns and mental illness, gun-related suicides are an overlooked issue that takes more than 20,000 lives each year.”

Related Links:

— “We need to rethink mental health laws. But not because of mass shootings.,” Nathaniel Morris, Washington Post, March 2, 2018.

In Wake Of Falling Milk Prices, Dairy Cooperative Acts To Prevent Suicides Among Its Members

The AP (3/3, Rathke) reported that last month, the Agri-Mark dairy cooperative sent “a list of mental health services and the number of a suicide prevention hotline” to its 1,000 New England and New York farmer members who are under financial and psychological stress due to falling milk prices. According to the article, “a 2016 Centers for Disease Control and Prevention report” found that “people working in farming, fishing and forestry had the highest rate of suicide.”

Related Links:

— “Milk co-op mailing highlights suicide risk for dairy farmers,” LISA RATHKE, Associated Press, March 3, 2018.

Central Hearing Loss May Share Same Mechanism Of Neurodegeneration With Cognitive Decline

Medscape (3/2, Anderson) reported that “central hearing loss may share the same mechanism of neurodegeneration with cognitive decline,” research indicated. The 1,604-participant “study showed that patients with central hearing loss, or central presbycusis, were twice as likely to have mild cognitive impairment (MCI) as those with no hearing loss, but there was no association between age-related hearing loss, or peripheral presbycusis, and cognitive impairment.” The study is scheduled for presentation during the upcoming American Academy of Neurology 2018 Annual Meeting.

Related Links:

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Researcher Finds New Gene Variant Robustly Linked to Opioid Addiction

Medscape (3/1, Brooks) reports, “Researchers have identified a novel gene variant involved in opioid addiction, a finding that may aid efforts to develop novel pharmacologic approaches to the treatment of opioid dependence.” Medscape reports that in a genome-wide association study, “investigators found that a variant on chromosome 15 (rs12442138) near the repulsive guidance molecule A (RGMA) gene was associated with opioid dependence at a ‘genome-wide significant’ level.” The study was published online in Biological Psychiatry.

Related Links:

Medscape (requires login and subscription)

Growing Number Of Women Taking Class C AD/HD Medications

The Hartford (CT) Courant (3/1, Rosner) reports, “The number of privately insured women nationwide between the ages of 15 and 44 who filled a prescription for an” attention-deficit/hyperactivity disorder AD/HD “medication soared 344 percent from 2003 to 2015, from 0.9 percent to 4 percent, according to” data from the Centers for Disease Control and Prevention (CDC).

Amphetamine salts, lisdexamfetamine, and methylphenidate are the three commonly filled AD/HD prescriptions, according to the CDC, and all three of those drugs are classified as Category C drugs by the FDA, which means that “studies on animals have shown an adverse effect on a fetus and there are no adequate and well-controlled studies in humans, but potential benefit may warrant their use in pregnancy despite potential risks.”

Related Links:

— “ADHD Drug Use Rises Sharply Among Young Women,” Cara Rosner, , March 1, 2018.