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Addressing Alienation Can Improve Psychosocial Outcomes In Pediatric Patients With Cancer, Review Suggests
Oncology Nurse Advisor (2/12, Garlapow) reports a systematic review of 30 studies found that “alienation is a profound and multidimensional consequence of childhood and adolescent cancer that warrants clinical recognition alongside physical morbidity.” The review included data “derived from 980 respondents aged 1 to 29 years and encompassed diverse cancer types, most commonly leukemia, lymphoma, central nervous system tumors, sarcoma, and other solid tumors.” The meta-aggregation yielded 4 synthesized findings and 13 categories: environmental alienation, self-alienation, interpersonal alienation, and social alienation. Researchers concluded that pediatric healthcare professionals “should adopt a person-centered approach that values the ‘voices’ of children and adolescents, supports the rebuilding of social connections and the continuity of identity, and promotes meaningful societal participation during and beyond cancer treatment.” The review was published in the Journal of Adolescence.
Related Links:
— “Addressing Alienation Can Improve Psychosocial Outcomes in Pediatric Cancer,”Megan Garlapow, PhD, Oncology Nurse Advisor, February 12, 2026
Antidepressant Discontinuation By Pregnant Patients Linked To Higher Mental Health Emergency Risk, Study Suggests
HealthDay (2/12, Thompson) reports a study presented at The Pregnancy Meeting suggests that “pregnant women who quit their antidepressants are nearly twice as likely to experience a mental health emergency compared to those who keep taking their meds.” The researchers “tracked insurance health records for nearly 4,000 women who gave birth in 2023 and 2024. All were diagnosed with depression or anxiety prior to pregnancy.” They found that “of those patients, 37% entered pregnancy with a prescription for an antidepressant. About 18% had no prescription fills during their pregnancy, and 65% had a gap of more than 60 days in fills.” Study results indicated that “women who quit their antidepressants had nearly double the risk for a mental health problem such as suicidal thoughts, substance overdose or psychosis. The risk peaked in the first and ninth months of pregnancy, researchers found.”
Related Links:
— “Antidepressant Discontinuation By Pregnant Patients Linked To Higher Mental Health Emergency Risk, Study Suggests,”Dennis Thompson , HealthDay , February 12, 2026
Wearable Devices May Be Able To Predict Depression Relapse Weeks Before Symptoms Emerge, Study Suggests
HealthDay (2/12, Neff) reports a study “suggests that wearable trackers can detect the subtle signs of a depression relapse weeks or even months before an actual episode.” The study followed 93 Canadian adults with “a diagnosis of major depressive disorder and had previously recovered from a depression episode” for up to two years. The participants “wore a research-grade device similar to a Fitbit or Apple Watch around the clock and had regular in-person visits for depression assessment and data download.” Researchers observed that “a person’s daily rhythms tell a story. Specifically, people with irregular sleep schedules had nearly double the risk of falling back into a depressive episode. The most telling sign wasn’t just how long someone slept, but how different their day was from their night.” Specifically, “when the data showed less of a difference between daytime movement and nighttime rest, a relapse was often right around the corner.” The study was published in JAMA Psychiatry.
Related Links:
— “Smartwatches May Soon Predict a Depression Relapse,”Deanna Neff, HealthDay , February 12, 2026
Drug Overdoses, Violence Accounted For More Than A Quarter Of All Deaths Among Pregnant And Postpartum Women In 2018-2023, Research Finds In the US
MedPage Today (2/11, Firth) reports, “Drug overdoses, homicides, and suicides accounted for more than a quarter of all deaths among pregnant and postpartum women, an analysis of maternal deaths from 2018 through 2023 showed.” Researchers found that “among 7,901 maternal deaths over this 6-year period, the leading cause was unintentional drug overdose, accounting for 1,152 deaths (5.2 deaths per 100,000 live births), followed by violence, defined as homicide or suicide (866 deaths; 3.9 deaths per 100,000 live births).” They noted that “altogether, homicides accounted for 68% of all violent deaths, and firearms were involved in 77% of homicides and 39% of suicides.” Furthermore, “violence and overdose accounted for 2,018 deaths, while the next four most common causes of death – cardiovascular causes, hypertension, infection, and hemorrhage – together accounted for 2,141 deaths.” The findings were published in the New England Journal of Medicine.
Related Links:
— MedPage Today (requires login and subscription)
Greater Everyday Discrimination Is Linked To Worse Patient-Reported Lupus Activity And Symptom Burden, But These Relationships Are Mediated By Depression And Anxiety Symptoms, Analysis Indicates
Rheumatology Advisor (2/10, Kuhns) reports, “Greater everyday discrimination is associated with worse patient-reported lupus activity and symptom burden, but these relationships are mediated by depression and anxiety symptoms, according to study results.” Investigators came to this conclusion after conducting an analysis that “included data collected between 2020 and 2021 from adults with physician-confirmed SLE in the San Francisco Bay Area.” The findings were published in The Journal of Rheumatology.
Related Links:
— “Discrimination Worsens SLE Symptom Burden Through Depression and Anxiety,”Lisa Kuhns, PhD, Rheumatology Advisor, February 10, 2026
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